Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9BQ69 / MACD1_HUMAN
Protein Name ADP-ribose glycohydrolase MACROD1
Gene Name Name: MACROD1
Synonyms:LRP16;
Organism Homo sapiens (Human)

PRO ID PR:Q9BQ69
DAG View
PRO Name ADP-ribose glycohydrolase MACROD1 (human)
Definition An ADP-ribose glycohydrolase MACROD1 that is encoded in the genome of human.
Short Label hMACROD1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9BQ69 (MACROD1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T91 O-Glycosylation GlyGen 25813380
K96 Acetylation PhosphoSitePlus
K96 Ubiquitination PhosphoSitePlus
K103 Acetylation PhosphoSitePlus
K138 Sumoylation PhosphoSitePlus
K163 Acetylation PhosphoSitePlus
C199 S-Nitrosylation dbSNO 26338901
R244 Methylation PhosphoSitePlus
C246 S-Nitrosylation dbSNO 26338901
K309 Acetylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T91 N91 Biomuta DOID:3571 / liver cancer [ cosmic ]
R244 H244 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
C246 Y246 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
C246 * Biomuta DOID:1612 / breast cancer [ cosmic ]