iPTMnet Report for Q99567 (NUP88)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q99567 / NUP88_HUMAN
Protein Name Nuclear pore complex protein Nup88
Gene Name Name: NUP88
Organism Homo sapiens (Human)

PRO ID PR:Q99567
DAG View
PRO Name nuclear pore complex protein Nup88 (human)
Definition A nuclear pore complex protein Nup88 that is encoded in the genome of human.
Short Label hNUP88
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q99567 (NUP88) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 22223895
S35 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18691976, 23186163, 19691289, ...18452278, 18669648, 20068231
T37 Phosphorylation HPRD   PhosphoSitePlus 20068231
K41 Ubiquitination PhosphoSitePlus
S45 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648
S46 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648
S49 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18691976, 18669648
S50 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18691976, 18669648, 23186163, ...20068231
T57 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648
S96 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 17525332
C103 Methylation IEDB 31844290
K138 Ubiquitination PhosphoSitePlus
K142 Ubiquitination PhosphoSitePlus
K150 Ubiquitination PhosphoSitePlus
C155 S-Nitrosylation dbSNO 2212679, 22126794
T166 Phosphorylation HPRD 20068231
S167 Phosphorylation HPRD 18691976
S168 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648, 19664995, 20068231, ...19691289
T169 Phosphorylation HPRD   PhosphoSitePlus 20068231
S170 Phosphorylation HPRD   phospho.ELM 18669648
T209 Phosphorylation PhosphoSitePlus
S221 Phosphorylation PhosphoSitePlus
K226 Ubiquitination PhosphoSitePlus
T231 Phosphorylation PhosphoSitePlus
S233 Phosphorylation PhosphoSitePlus
S379 Phosphorylation PhosphoSitePlus   UniProt 23186163
S387 Phosphorylation PhosphoSitePlus
K394 Ubiquitination PhosphoSitePlus
K400 Ubiquitination PhosphoSitePlus
K426 Ubiquitination PhosphoSitePlus
S430 Phosphorylation PhosphoSitePlus
K435 Ubiquitination PhosphoSitePlus
S437 Phosphorylation PhosphoSitePlus   UniProt 23186163
S442 Phosphorylation HPRD   PhosphoSitePlus   UniProt 19413330, 23186163, 20068231, ...18691976
T443 Phosphorylation PhosphoSitePlus
K456 Ubiquitination PhosphoSitePlus
S496 Phosphorylation PhosphoSitePlus
T497 Phosphorylation PhosphoSitePlus
S517 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18691976, 21406692, 19691289, ...23186163, 16964243, 18767875, 19664994, 19664995, 18452278, 19651622, 17322306, 18669648, 19690332, 19415658, 20068231, 17081983
T525 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18691976, 23186163, 16964243, ...19664995, 19691289, 19651622, 18669648, 19415658, 20068231
S528 Phosphorylation PhosphoSitePlus
K531 Ubiquitination PhosphoSitePlus
S540 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648, 19691289, 20068231
K548 Ubiquitination PhosphoSitePlus
K552 Ubiquitination PhosphoSitePlus
C561 Methylation IEDB 31844290
K579 Ubiquitination PhosphoSitePlus
K584 Acetylation PhosphoSitePlus
K584 Ubiquitination PhosphoSitePlus
K592 Acetylation PhosphoSitePlus
K592 Ubiquitination PhosphoSitePlus
K598 Ubiquitination PhosphoSitePlus
K600 Ubiquitination PhosphoSitePlus
S606 Phosphorylation PhosphoSitePlus
K625 Ubiquitination PhosphoSitePlus
K630 Ubiquitination PhosphoSitePlus
K642 Ubiquitination PhosphoSitePlus
S646 Phosphorylation HPRD   PhosphoSitePlus 19562805
S655 Phosphorylation PhosphoSitePlus
K663 Ubiquitination PhosphoSitePlus
K680 Ubiquitination PhosphoSitePlus
Y688 Phosphorylation PhosphoSitePlus
K692 Ubiquitination PhosphoSitePlus
K695 Ubiquitination PhosphoSitePlus
K712 Ubiquitination PhosphoSitePlus
K719 Ubiquitination PhosphoSitePlus
K730 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S221 R221 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S233 F233 Biomuta DOID:1319 / brain cancer [ cosmic ]
K400 N400 Biomuta DOID:1319 / brain cancer [ cosmic ]
T443 A443 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S528 F528 Biomuta [ cosmic ]
K531 N531 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
K598 * Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S606 G606 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S646 R646 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
S655 F655 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
K695 N695 Biomuta DOID:9256 / colorectal cancer [ cosmic ]