iPTMnet Report for Q99471 (PFDN5)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q99471 / PFD5_HUMAN
Protein Name Prefoldin subunit 5
Gene Name Name: PFDN5
Synonyms:MM1,PFD5;
Organism Homo sapiens (Human)

PRO ID PR:Q99471
DAG View
PRO Name prefoldin subunit 5 (human)
Definition A prefoldin subunit 5 that is encoded in the genome of human.
Short Label hPFDN5
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q99471 (PFDN5) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 19413330, 22223895
S4 Phosphorylation PhosphoSitePlus
K42 Acetylation PhosphoSitePlus   UniProt 19608861
K42 Ubiquitination PhosphoSitePlus
K47 Acetylation PhosphoSitePlus
K47 Ubiquitination PhosphoSitePlus
C49 Methylation IEDB 31844290
K55 Ubiquitination PhosphoSitePlus
S56 Phosphorylation PhosphoSitePlus   UniProt 23186163
K60 Ubiquitination PhosphoSitePlus
Y90 Phosphorylation PhosphoSitePlus
Y91 Phosphorylation PhosphoSitePlus
K100 Ubiquitination PhosphoSitePlus
K104 Ubiquitination PhosphoSitePlus
K112 Acetylation PhosphoSitePlus
K112 Ubiquitination PhosphoSitePlus
K124 Ubiquitination PhosphoSitePlus
K153 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
A2 S2 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S4 F4 Biomuta DOID:2394 / ovarian cancer [ cosmic, icgc ]
K47 * Biomuta DOID:3571 / liver cancer [ cosmic ]
S56 N56 Biomuta DOID:1319 / brain cancer [ cosmic ]
Y90 H90 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K100 N100 Biomuta DOID:363 / uterine cancer [ icgc ]