iPTMnet Report for Q99426 (TBCB)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q99426 / TBCB_HUMAN
Protein Name Tubulin-folding cofactor B
Gene Name Name: TBCB
Synonyms:CG22,CKAP1;
Organism Homo sapiens (Human)

PRO ID PR:Q99426
DAG View
PRO Name tubulin-folding cofactor B (human)
Definition A tubulin-folding cofactor B that is encoded in the genome of human.
Short Label hTBCB
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q99426 (TBCB) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
M1 Acetylation UniProt 22223895
S29 Phosphorylation IEDB 29493099
S31 Phosphorylation PhosphoSitePlus
T33 Phosphorylation PhosphoSitePlus
S65 Phosphorylation Q13153 (PAK1) phospho.ELM   PhosphoSitePlus   Signor   UniProt 15831477
K66 Ubiquitination PhosphoSitePlus
C83 Methylation IEDB 31844290
S91 Phosphorylation PhosphoSitePlus
Y98 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 15592455, 18083107, 15144186
S102 Phosphorylation PhosphoSitePlus
K106 Ubiquitination PhosphoSitePlus
Y107 Phosphorylation PhosphoSitePlus
T108 Phosphorylation PhosphoSitePlus
S110 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 17525332, 23186163
Y114 Phosphorylation phospho.ELM   PhosphoSitePlus 15592455
T120 Phosphorylation PhosphoSitePlus
S123 Phosphorylation PhosphoSitePlus
S128 Phosphorylation Q13153 (PAK1) phospho.ELM   PhosphoSitePlus   Signor   UniProt 15831477
Y133 Phosphorylation PhosphoSitePlus
K153 Acetylation PhosphoSitePlus
K153 Ubiquitination PhosphoSitePlus
C165 S-Nitrosylation dbSNO 26338901
S173 Phosphorylation PhosphoSitePlus
K188 Ubiquitination PhosphoSitePlus
K203 Ubiquitination PhosphoSitePlus
K211 Ubiquitination PhosphoSitePlus
K219 Acetylation PhosphoSitePlus   UniProt 19608861
K219 Ubiquitination PhosphoSitePlus
Y239 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S91 Phosphorylation HPRD 20068231
Y98 Phosphorylation HPRD 19901323, 15144186, 18707149
S110 Phosphorylation HPRD 17525332, 18077418
Y114 Phosphorylation HPRD 15592455
S173 Phosphorylation HPRD 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S65 G65 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
S91 N91 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S102 F102 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
Y107 F107 Biomuta DOID:263 / kidney cancer [ cosmic ]
Y239 * Biomuta DOID:4159 / skin cancer [ cosmic ]