iPTMnet Report for Q96T37 (RBM15)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q96T37 / RBM15_HUMAN
Protein Name RNA-binding protein 15
Gene Name Name: RBM15
Synonyms:OTT;
Organism Homo sapiens (Human)

PRO ID PR:Q96T37
DAG View
PRO Name RNA-binding protein 15 (human)
Definition An RNA-binding protein 15 that is encoded in the genome of human.
Short Label hRBM15
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q96T37 (RBM15) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T32 Phosphorylation PhosphoSitePlus
S51 Phosphorylation phospho.ELM   PhosphoSitePlus 17081983
S80 Phosphorylation PhosphoSitePlus
S83 Phosphorylation phospho.ELM   PhosphoSitePlus 15302935
S84 Phosphorylation PhosphoSitePlus
S97 Phosphorylation PhosphoSitePlus
S103 Phosphorylation PhosphoSitePlus
S105 Phosphorylation PhosphoSitePlus
S109 Phosphorylation PhosphoSitePlus   UniProt 21406692, 20068231, 24275569
R110 Methylation PhosphoSitePlus
Y112 Phosphorylation PhosphoSitePlus
S118 Phosphorylation PhosphoSitePlus
S125 Phosphorylation phospho.ELM   PhosphoSitePlus 15302935
Y126 Phosphorylation PhosphoSitePlus
S127 Phosphorylation PhosphoSitePlus
S128 Phosphorylation phospho.ELM   PhosphoSitePlus 15302935
S130 Phosphorylation PhosphoSitePlus
T131 Phosphorylation PhosphoSitePlus
S134 Phosphorylation PhosphoSitePlus
S135 Phosphorylation PhosphoSitePlus
S140 Phosphorylation PhosphoSitePlus
S143 Phosphorylation PhosphoSitePlus
S151 Phosphorylation PhosphoSitePlus
S153 Phosphorylation PhosphoSitePlus
S154 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
K170 Sumoylation PhosphoSitePlus
K170 Ubiquitination PhosphoSitePlus
S175 Phosphorylation PhosphoSitePlus
S179 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 17525332, 23186163, 18669648
S182 Phosphorylation PhosphoSitePlus
K195 Ubiquitination PhosphoSitePlus
S201 Phosphorylation PhosphoSitePlus
S205 Phosphorylation PhosphoSitePlus
S208 Phosphorylation PhosphoSitePlus   UniProt 23186163
S210 Phosphorylation PhosphoSitePlus   UniProt 20068231
S212 Phosphorylation PhosphoSitePlus
Y251 Phosphorylation PhosphoSitePlus
S253 Phosphorylation PhosphoSitePlus   UniProt 23186163
S257 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 20068231, ...24275569
S259 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 20068231, ...24275569
T265 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
Y266 Phosphorylation PhosphoSitePlus   UniProt 24275569
S269 Phosphorylation PhosphoSitePlus
S271 Phosphorylation PhosphoSitePlus
S276 Phosphorylation PhosphoSitePlus
S292 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 17081983, 18220336, ...18669648, 24275569
S294 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 23186163, 16964243, ...18220336, 15302935, 18669648, 24275569, 20068231, 17081983
Y336 Phosphorylation PhosphoSitePlus
R340 Methylation PhosphoSitePlus
Y343 Phosphorylation PhosphoSitePlus
S344 Phosphorylation PhosphoSitePlus
R348 Methylation PhosphoSitePlus
S365 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 16964243, 20068231
T384 Phosphorylation PhosphoSitePlus
T401 O-Glycosylation GlyGen 34019948, 25367160, 30620550
K406 Ubiquitination PhosphoSitePlus
Y416 Phosphorylation PhosphoSitePlus
K420 Methylation PhosphoSitePlus
K420 Sumoylation PhosphoSitePlus
K445 Ubiquitination PhosphoSitePlus
K450 Acetylation PhosphoSitePlus   UniProt 19608861
T480 Phosphorylation PhosphoSitePlus
Y537 Phosphorylation PhosphoSitePlus
T544 Phosphorylation PhosphoSitePlus
Y546 Phosphorylation PhosphoSitePlus
T550 Phosphorylation PhosphoSitePlus
T568 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 23186163, 17081983, ...18220336, 18669648, 24275569, 20068231
R578 Methylation PhosphoSitePlus   UniProt 26575292
Y581 Phosphorylation PhosphoSitePlus
S584 Phosphorylation PhosphoSitePlus
S604 Phosphorylation PhosphoSitePlus
Y608 Phosphorylation PhosphoSitePlus
S613 Phosphorylation PhosphoSitePlus
S622 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 17081983, 20068231
S635 Phosphorylation PhosphoSitePlus
S648 Phosphorylation PhosphoSitePlus
S656 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 17287340, 18669648, 23186163
S659 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S670 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 17081983, 18220336, ...18669648, 24275569, 19690332, 20068231
S674 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 17081983, 18220336, ...18669648, 24275569, 19690332
S678 Phosphorylation phospho.ELM   PhosphoSitePlus 17081983, 18220336
S679 Phosphorylation phospho.ELM   PhosphoSitePlus 17081983, 18220336
S680 Phosphorylation PhosphoSitePlus
Y684 Phosphorylation PhosphoSitePlus
S686 Phosphorylation PhosphoSitePlus
S691 Phosphorylation PhosphoSitePlus
S692 O-Glycosylation GlyGen 34019948, 25367160, 30620550
S692 Phosphorylation PhosphoSitePlus
S700 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 17081983, ...24275569
S708 Phosphorylation phospho.ELM   PhosphoSitePlus 17081983
S712 Phosphorylation PhosphoSitePlus
S722 Phosphorylation PhosphoSitePlus
S724 Phosphorylation phospho.ELM   PhosphoSitePlus 17081983
T733 Phosphorylation PhosphoSitePlus
T734 Phosphorylation PhosphoSitePlus
T737 Phosphorylation PhosphoSitePlus
S741 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 23186163, 18669648, ...24275569, 17287340
S757 O-Glycosylation GlyGen 34019948, 25367160, 30620550
K762 Acetylation PhosphoSitePlus
S765 Phosphorylation PhosphoSitePlus   UniProt 21406692, 23186163, 20068231
S767 Phosphorylation PhosphoSitePlus   UniProt 23186163
T774 Phosphorylation PhosphoSitePlus
S779 Phosphorylation PhosphoSitePlus
S781 Phosphorylation PhosphoSitePlus   UniProt 23186163
K841 Ubiquitination PhosphoSitePlus
K850 Ubiquitination PhosphoSitePlus
S878 Phosphorylation PhosphoSitePlus
S893 Phosphorylation PhosphoSitePlus
S929 Phosphorylation PhosphoSitePlus
S935 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 20068231
K938 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S51 Phosphorylation HPRD 17081983, 20068231
S83 Phosphorylation HPRD 15302935
S97 Phosphorylation HPRD 20068231
S109 Phosphorylation HPRD 20068231, 18452278
S125 Phosphorylation HPRD 15302935, 20068231
S127 Phosphorylation HPRD 19651622, 20068231
S128 Phosphorylation HPRD 15302935, 20068231
T131 Phosphorylation HPRD 20068231
S140 Phosphorylation HPRD 19413330
S154 Phosphorylation HPRD 19413330, 18669648
S179 Phosphorylation HPRD 17525332, 18669648
S210 Phosphorylation HPRD 20068231
S257 Phosphorylation HPRD 19651622, 20166139, 18669648, ...20068231, 20230923
S259 Phosphorylation HPRD 20230923, 18452278, 19651622, ...18669648, 20166139, 20068231
T265 Phosphorylation HPRD 18669648, 20230923
Y266 Phosphorylation HPRD 20230923
S292 Phosphorylation HPRD 19413330, 18669648, 20058876, ...17081983, 20068231
S294 Phosphorylation HPRD 19413330, 18691976, 18491316, ...16964243, 19562805, 18767875, 20058876, 19691289, 19664995, 17322306, 18669648, 19651622, 18707149, 20166139, 18452278, 19415658, 20068231, 18212344
S365 Phosphorylation HPRD 20068231
T568 Phosphorylation HPRD 17322306, 18212344, 18767875, ...20058876, 19664995, 18452278, 19651622, 18669648, 20166139, 20068231, 20068230
S622 Phosphorylation HPRD 19651622, 17081983, 20068231
S634 Phosphorylation HPRD 17081983
S656 Phosphorylation HPRD 17322306, 17287340, 18767875, ...19651622, 18669648, 20068231
S659 Phosphorylation HPRD 18669648, 17081983, 20068231, ...17924679
S670 Phosphorylation HPRD 17322306, 18212344, 19651622, ...18669648, 20166139, 20068231
S674 Phosphorylation HPRD 17322306, 18212344, 19651622, ...18669648, 20166139, 20068231
S678 Phosphorylation HPRD 19651622, 17081983
S679 Phosphorylation HPRD 19651622, 17081983
S680 Phosphorylation HPRD 19651622, 17081983, 20068231
S700 Phosphorylation HPRD 18691976, 18767875, 20058876, ...19664995, 18452278, 19651622, 17322306, 18669648, 20166139, 20068231
S708 Phosphorylation HPRD 17081983, 20068231
S724 Phosphorylation HPRD 17081983
T737 Phosphorylation HPRD 18767875
S741 Phosphorylation HPRD 17322306, 17287340, 19664995, ...18452278, 19651622, 18669648, 20068231
S765 Phosphorylation HPRD 20068231
S779 Phosphorylation HPRD 19664995, 20068231
S781 Phosphorylation HPRD 19413330, 19664995, 20068231
S935 Phosphorylation HPRD 18669648, 20068231, 18452278


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S80 N80 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:10283 / prostate cancer [ cosmic ]
S83 N83 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S103 F103 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S105 N105 Biomuta DOID:11054 / urinary bladder cancer [ icgc ]
Y126 C126 Biomuta DOID:1319 / brain cancer [ icgc ]
S127 N127 Biomuta DOID:4159 / skin cancer [ cosmic ]
S130 N130 Biomuta DOID:363 / uterine cancer [ icgc ] DOID:9256 / colorectal cancer [ cosmic ]
S134 Y134 Biomuta DOID:1793 / pancreatic cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ]
S135 * Biomuta DOID:1612 / breast cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic ]
S153 F153 Biomuta DOID:4159 / skin cancer [ cosmic ]
S154 F154 Biomuta DOID:2394 / ovarian cancer [ cosmic, icgc ]
S182 N182 Biomuta DOID:184 / bone cancer [ cosmic ]
S205 C205 Biomuta DOID:4606 / bile duct cancer [ cosmic ]
S208 L208 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S212 R212 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
Y251 H251 Biomuta DOID:363 / uterine cancer [ icgc ]
S271 G271 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S271 N271 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
R348 M348 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]
R348 G348 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S365 L365 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
K445 T445 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
T480 I480 Biomuta DOID:4159 / skin cancer [ cosmic ]
T544 S544 Biomuta DOID:263 / kidney cancer [ cosmic, icgc ]
Y581 C581 Biomuta DOID:5041 / esophageal cancer [ cosmic, icgc ]
S584 F584 Biomuta [ cosmic ]
S648 G648 Biomuta DOID:2394 / ovarian cancer [ cosmic ]
S656 Y656 Biomuta DOID:1612 / breast cancer [ cosmic ]
S670 F670 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic, icgc ] DOID:11934 / head and neck cancer [ icgc ]
Y684 * Biomuta DOID:1324 / lung cancer [ cosmic ]
S686 N686 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S692 F692 Biomuta DOID:4159 / skin cancer [ cosmic ]
S722 T722 Biomuta DOID:10283 / prostate cancer [ cosmic ]
T734 S734 Biomuta DOID:263 / kidney cancer [ cosmic ]
S757 G757 Biomuta DOID:4159 / skin cancer [ cosmic ]
S765 Y765 Biomuta DOID:1324 / lung cancer [ cosmic ]
T774 K774 Biomuta DOID:1793 / pancreatic cancer [ cosmic ]
K938 N938 Biomuta DOID:3571 / liver cancer [ cosmic ]