iPTMnet Report for Q96QR8 (PURB)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q96QR8 / PURB_HUMAN
Protein Name Transcriptional activator protein Pur-beta
Gene Name Name: PURB
Organism Homo sapiens (Human)

PRO ID PR:Q96QR8
DAG View
PRO Name transcriptional activator protein Pur-beta (human)
Definition A transcriptional activator protein Pur-beta that is encoded in the genome of human.
Short Label hPURB
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q96QR8 (PURB) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 19413330, 21406692, 20068231
S6 Phosphorylation HPRD   PhosphoSitePlus   UniProt 19413330, 23186163, 17081983, ...19651622, 20068231
S8 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19413330, 23186163, 17081983, ...19651622, 20068231
C17 S-Nitrosylation dbSNO 26338901
S23 Phosphorylation PhosphoSitePlus
Y47 Phosphorylation PhosphoSitePlus
K60 Ubiquitination PhosphoSitePlus
S69 Phosphorylation PhosphoSitePlus
K70 Ubiquitination PhosphoSitePlus
S86 Phosphorylation PhosphoSitePlus
S100 Phosphorylation HPRD   PhosphoSitePlus 19651622, 17081983, 20068231
S101 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19651622, 23186163, 17081983, ...18220336, 15302935, 18452278, 17322306, 18669648, 19690332, 20068231
K120 Ubiquitination PhosphoSitePlus
S121 Phosphorylation PhosphoSitePlus
K130 Acetylation PhosphoSitePlus
K136 Methylation PhosphoSitePlus
K136 Ubiquitination PhosphoSitePlus
R152 Methylation PhosphoSitePlus
C238 Methylation IEDB 31844290
Y241 Phosphorylation PhosphoSitePlus
K251 Ubiquitination PhosphoSitePlus
S253 Phosphorylation PhosphoSitePlus
Y254 Phosphorylation PhosphoSitePlus
K263 Ubiquitination PhosphoSitePlus
K267 Acetylation PhosphoSitePlus
K267 Ubiquitination PhosphoSitePlus
Y291 Phosphorylation PhosphoSitePlus
S298 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 21406692, 18669648, 19690332, ...17081983
S304 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 17322306, 21406692, 23186163, ...18212344, 15302935, 18318008, 19651622, 18669648, 20166139, 19415658, 20068231, 17081983


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S8 G8 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
S23 F23 Biomuta DOID:4606 / bile duct cancer [ cosmic ]
S298 R298 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S298 G298 Biomuta DOID:10534 / stomach cancer [ cosmic ]