iPTMnet Report for Q96PU4 (UHRF2)
Protein Information
UniProt AC / UniProt ID | Q96PU4 / UHRF2_HUMAN |
Protein Name | E3 ubiquitin-protein ligase UHRF2 |
Gene Name | Name: UHRF2 Synonyms:NIRF,RNF107; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q96PU4 |
PRO Name | E3 ubiquitin-protein ligase UHRF2 (human) |
Definition | An E3 ubiquitin-protein ligase UHRF2 that is encoded in the genome of human. |
Short Label | hUHRF2 |
Category | organism-gene |
Q96PU4 (UHRF2) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
K12 | Acetylation | score1 | PhosphoSitePlus | |||
K12 | Ubiquitination | score1 | PhosphoSitePlus | |||
C14 | Methylation | score1 | IEDB | 31844290 | ||
K22 | Ubiquitination | score1 | PhosphoSitePlus | |||
S95 | Phosphorylation | score1 | PhosphoSitePlus | |||
S108 | Phosphorylation | score1 | PhosphoSitePlus | |||
K128 | Ubiquitination | score1 | PhosphoSitePlus | |||
K238 | Sumoylation | score1 | PhosphoSitePlus | |||
S290 | Phosphorylation | score1 | PhosphoSitePlus | |||
K307 | Ubiquitination | score1 | PhosphoSitePlus | |||
K322 | Ubiquitination | score1 | PhosphoSitePlus | |||
K393 | Ubiquitination | score1 | PhosphoSitePlus | |||
K401 | Sumoylation | score1 | PhosphoSitePlus | |||
K401 | Ubiquitination | score1 | PhosphoSitePlus | |||
R428 | Methylation | score1 | PhosphoSitePlus | |||
K519 | Ubiquitination | score1 | PhosphoSitePlus | |||
K548 | Ubiquitination | score1 | PhosphoSitePlus | |||
K575 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y584 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y588 | Phosphorylation | score1 | PhosphoSitePlus | |||
K589 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y641 | Phosphorylation | score1 | PhosphoSitePlus | |||
S643 | Phosphorylation | score1 | PhosphoSitePlus | |||
S654 | Phosphorylation | score1 | PhosphoSitePlus | |||
S659 | Phosphorylation | score1 | PhosphoSitePlus | |||
T661 | Phosphorylation | score1 | PhosphoSitePlus | |||
T662 | Phosphorylation | score1 | PhosphoSitePlus | |||
K663 | Ubiquitination | score1 | PhosphoSitePlus | |||
S667 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 18669648 | ||
S673 | Phosphorylation | score1 | PhosphoSitePlus | |||
K676 | Ubiquitination | score1 | PhosphoSitePlus | |||
K679 | Ubiquitination | score1 | PhosphoSitePlus | |||
S683 | Phosphorylation | score1 | PhosphoSitePlus | |||
K708 | Ubiquitination | score1 | PhosphoSitePlus | |||
C748 | Methylation | score1 | IEDB | 31844290 |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
K322 | N322 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
K519 | T519 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] | |
K575 | E575 | Biomuta | DOID:4362 / cervical cancer [ icgc ] | |
Y584 | * | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] | |
S667 | * | Biomuta | DOID:1612 / breast cancer [ cosmic ] | |
K679 | T679 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] |