iPTMnet Report for Q96M69 (LRGUK)
Protein Information
UniProt AC / UniProt ID | Q96M69 / LRGUK_HUMAN |
Protein Name | Leucine-rich repeat and guanylate kinase domain-containing protein |
Gene Name | Name: LRGUK |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q96M69 |
PRO Name | leucine-rich repeat and guanylate kinase domain-containing protein (human) |
Definition | A leucine-rich repeat and guanylate kinase domain-containing protein that is encoded in the genome of human. |
Short Label | hLRGUK |
Category | organism-gene |
Q96M69 (LRGUK) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S15 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y322 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 17924679 | ||
Y529 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y540 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y543 | Phosphorylation | score1 | PhosphoSitePlus | |||
S560 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S15 | T15 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] | |
Y322 | C322 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic, icgc ] | |
S560 | Y560 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] |