iPTMnet Report for Q96LC7 (SIGLEC10)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q96LC7 / SIG10_HUMAN
Protein Name Sialic acid-binding Ig-like lectin 10 precursor
Gene Name Name: SIGLEC10
Synonyms:SLG2;ORFNames:UNQ477/PRO940;
Organism Homo sapiens (Human)

PRO ID PR:Q96LC7
DAG View
PRO Name sialic acid-binding Ig-like lectin 10 (human)
Definition A sialic acid-binding Ig-like lectin 10 that is encoded in the genome of human.
Short Label hSIGLEC10
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q96LC7 (SIGLEC10) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S8 Phosphorylation PhosphoSitePlus
S9 Phosphorylation PhosphoSitePlus
S38 Phosphorylation PhosphoSitePlus
Y57 Phosphorylation PhosphoSitePlus
N100 N-Glycosylation GlyGen 24190977
T250 Phosphorylation PhosphoSitePlus
T322 Phosphorylation PhosphoSitePlus
S331 Phosphorylation PhosphoSitePlus
S339 Phosphorylation PhosphoSitePlus
N355 N-Glycosylation GlyGen 24190977
N361 N-Glycosylation GlyGen 24190977
N364 N-Glycosylation GlyGen 24190977
S589 Phosphorylation PhosphoSitePlus
S592 Phosphorylation PhosphoSitePlus
T593 Phosphorylation PhosphoSitePlus
Y597 Phosphorylation neXtProt   phospho.ELM   PhosphoSitePlus   Signor 11733002
Y597 Phosphorylation P06239 (LCK) phospho.ELM   PhosphoSitePlus   Signor 11733002
Y597 Phosphorylation P52333 (JAK3) neXtProt   phospho.ELM   PhosphoSitePlus   Signor 11733002
Y597 Phosphorylation Q08881 (ITK) phospho.ELM   PhosphoSitePlus   Signor 11733002
S630 Phosphorylation PhosphoSitePlus
S645 Phosphorylation PhosphoSitePlus
Y667 Phosphorylation IntAct   neXtProt   phospho.ELM   PhosphoSitePlus   Signor   UniProt 11733002, 12163025
Y667 Phosphorylation P06239 (LCK) phospho.ELM   PhosphoSitePlus   Signor 11733002
Y667 Phosphorylation P06241 (FYN) PhosphoSitePlus 12163025
Y667 Phosphorylation P52333 (JAK3) neXtProt   phospho.ELM   PhosphoSitePlus   Signor 11733002
Y667 Phosphorylation Q08881 (ITK) phospho.ELM   PhosphoSitePlus   Signor 11733002
Y691 Phosphorylation phospho.ELM   PhosphoSitePlus   Signor 11733002
Y691 Phosphorylation P06239 (LCK) phospho.ELM   PhosphoSitePlus   Signor 11733002
Y691 Phosphorylation P52333 (JAK3) phospho.ELM   PhosphoSitePlus   Signor 11733002
Site PTM Type PTM Enzyme Score Source PMID
S298 Phosphorylation HPRD 18767875


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S9 L9 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
S38 A38 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T250 M250 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ] DOID:2531 / hematologic cancer [ cosmic ]
S298 Y298 Biomuta DOID:4159 / skin cancer [ cosmic ]
N355 K355 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
N364 K364 Biomuta DOID:1324 / lung cancer [ cosmic ]
T593 M593 Biomuta DOID:1324 / lung cancer [ cosmic ]
Y597 C597 Biomuta DOID:10534 / stomach cancer [ cosmic ]