iPTMnet Report for Q96JZ2 (HSH2D)
Protein Information
UniProt AC / UniProt ID | Q96JZ2 / HSH2D_HUMAN |
Protein Name | Hematopoietic SH2 domain-containing protein |
Gene Name | Name: HSH2D Synonyms:ALX; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q96JZ2 |
PRO Name | hematopoietic SH2 domain-containing protein (human) |
Definition | A hematopoietic SH2 domain-containing protein that is encoded in the genome of human. |
Short Label | hHSH2D |
Category | organism-gene |
Q96JZ2 (HSH2D) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
Y135 | Phosphorylation | score1 | PhosphoSitePlus | |||
S175 | Phosphorylation | score1 | PhosphoSitePlus | |||
S189 | Phosphorylation | score1 | PhosphoSitePlus | |||
S194 | Phosphorylation | score1 | PhosphoSitePlus | |||
S206 | Phosphorylation | score1 | PhosphoSitePlus | |||
K249 | Ubiquitination | score1 | PhosphoSitePlus | |||
S251 | Phosphorylation | score1 | PhosphoSitePlus | |||
S255 | Phosphorylation | score1 | PhosphoSitePlus | |||
T259 | Phosphorylation | score1 | PhosphoSitePlus | |||
S260 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y265 | Phosphorylation | score1 | PhosphoSitePlus | |||
K275 | Ubiquitination | score1 | PhosphoSitePlus | |||
S276 | Phosphorylation | score1 | PhosphoSitePlus | |||
S296 | Phosphorylation | score1 | PhosphoSitePlus | |||
S298 | Phosphorylation | score1 | PhosphoSitePlus | |||
S318 | Phosphorylation | score1 | PhosphoSitePlus | |||
S319 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
Y135 | N135 | Biomuta | DOID:2531 / hematologic cancer [ cosmic ] | |
S194 | Y194 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
S194 | P194 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
S194 | C194 | Biomuta | DOID:363 / uterine cancer [ cosmic ] | |
S194 | F194 | Biomuta | [ cosmic ] DOID:4159 / skin cancer [ cosmic ] | |
S206 | C206 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
T259 | I259 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
S260 | L260 | Biomuta | DOID:4159 / skin cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ] | |
S260 | * | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] | |
S298 | I298 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
S319 | F319 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
S319 | P319 | Biomuta | DOID:4159 / skin cancer [ cosmic ] |