iPTMnet Report for Q96JY6 (PDLIM2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q96JY6 / PDLI2_HUMAN
Protein Name PDZ and LIM domain protein 2
Gene Name Name: PDLIM2
ORFNames:PP6345;
Organism Homo sapiens (Human)

PRO ID PR:Q96JY6
DAG View
PRO Name PDZ and LIM domain protein 2 (human)
Definition A PDZ and LIM domain protein 2 that is encoded in the genome of human.
Short Label hPDLIM2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q96JY6 (PDLIM2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T25 Phosphorylation PhosphoSitePlus
T30 Phosphorylation PhosphoSitePlus
S72 Phosphorylation PhosphoSitePlus
S74 Phosphorylation PhosphoSitePlus
S83 Phosphorylation PhosphoSitePlus
S87 Phosphorylation PhosphoSitePlus
Y111 Phosphorylation PhosphoSitePlus
S114 Phosphorylation PhosphoSitePlus
S117 Phosphorylation PhosphoSitePlus
S120 Phosphorylation PhosphoSitePlus
S121 Phosphorylation PhosphoSitePlus
Y122 Phosphorylation PhosphoSitePlus
S123 Phosphorylation PhosphoSitePlus
S124 Phosphorylation PhosphoSitePlus   UniProt 24275569
T126 Phosphorylation PhosphoSitePlus   UniProt 24275569
S127 Phosphorylation PhosphoSitePlus
S129 Phosphorylation PhosphoSitePlus   UniProt 24275569
R131 Methylation PhosphoSitePlus
S134 O-Glycosylation GlyGen 34019948, 29351928, 35132862, ...35254053
S134 Phosphorylation PhosphoSitePlus
S137 O-Glycosylation GlyGen 34019948, 29351928, 35132862, ...35254053
S137 Phosphorylation PhosphoSitePlus   UniProt 24275569
S141 O-Glycosylation GlyGen 34019948, 29351928, 35132862, ...35254053
S141 Phosphorylation PhosphoSitePlus
S142 O-Glycosylation GlyGen 29351928, 34019948, 32938750, ...35132862, 35254053
S142 Phosphorylation PhosphoSitePlus
S143 O-Glycosylation GlyGen 34019948, 29351928, 35132862, ...35254053
S143 Phosphorylation PhosphoSitePlus
S144 O-Glycosylation GlyGen 34019948, 29351928, 35132862, ...35254053
S144 Phosphorylation PhosphoSitePlus
T146 O-Glycosylation GlyGen 34019948, 29351928, 35132862, ...35254053
T146 Phosphorylation PhosphoSitePlus
S152 O-Glycosylation GlyGen 34019948, 29351928, 35132862, ...35254053
S154 Phosphorylation PhosphoSitePlus
S157 Phosphorylation PhosphoSitePlus
S161 Phosphorylation PhosphoSitePlus   UniProt 24275569
R169 Methylation PhosphoSitePlus
S171 O-Glycosylation GlyGen 34019948, 29351928, 35132862, ...35254053
S171 Phosphorylation PhosphoSitePlus
Y172 Phosphorylation PhosphoSitePlus
S173 O-Glycosylation GlyGen 34019948, 29351928, 35132862, ...35254053
S173 Phosphorylation PhosphoSitePlus
S178 Phosphorylation PhosphoSitePlus
R185 Methylation PhosphoSitePlus
S189 Phosphorylation PhosphoSitePlus
S197 Phosphorylation PhosphoSitePlus   UniProt 19690332, 24275569
S202 Phosphorylation PhosphoSitePlus
S206 Phosphorylation PhosphoSitePlus
S209 Phosphorylation PhosphoSitePlus
S213 Phosphorylation PhosphoSitePlus
S220 Phosphorylation PhosphoSitePlus
S239 Phosphorylation PhosphoSitePlus
S240 Phosphorylation PhosphoSitePlus
S241 Phosphorylation PhosphoSitePlus
T257 Phosphorylation PhosphoSitePlus
S263 Phosphorylation PhosphoSitePlus
S264 Phosphorylation PhosphoSitePlus
S266 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648, 18220336
S269 Phosphorylation PhosphoSitePlus
T279 Phosphorylation PhosphoSitePlus
K282 Acetylation PhosphoSitePlus
C316 Methylation IEDB 31844290
Y342 Phosphorylation PhosphoSitePlus
S343 Phosphorylation PhosphoSitePlus
T347 O-Glycosylation GlyGen 31373491
S349 O-Glycosylation GlyGen 31373491
S350 O-Glycosylation GlyGen 31373491
Site PTM Type PTM Enzyme Score Source PMID
S124 Phosphorylation HPRD 20058876
T126 Phosphorylation HPRD 20166139
S129 Phosphorylation HPRD 20166139, 19664994, 20058876, ...19664995
S161 Phosphorylation HPRD 19664994, 19664995
S197 Phosphorylation HPRD 20058876, 19664995
S202 Phosphorylation HPRD 20166139
S266 Phosphorylation HPRD 19413330, 18669648, 20058876, ...20068231, 17924679
S365 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S124 Phosphorylation HPRD 20058876
T126 Phosphorylation HPRD 20166139
S129 Phosphorylation HPRD 20166139, 19664994, 20058876, ...19664995
S161 Phosphorylation HPRD 19664994, 19664995
S197 Phosphorylation HPRD 20058876, 19664995
S202 Phosphorylation HPRD 20166139


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T25 M25 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S83 C83 Biomuta DOID:4159 / skin cancer [ cosmic, icgc, cosmic, icgc ] DOID:1793 / pancreatic cancer [ cosmic, cosmic ] DOID:1324 / lung cancer [ cosmic, icgc ]
S121 T121 Biomuta DOID:3571 / liver cancer [ cosmic ]
S127 F127 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic, icgc ]
S129 N129 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S134 I134 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
S137 L137 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S144 F144 Biomuta DOID:4159 / skin cancer [ cosmic ]
S152 N152 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
S161 F161 Biomuta DOID:1793 / pancreatic cancer [ cosmic ]
R169 C169 Biomuta DOID:10534 / stomach cancer [ cosmic ]
R169 P169 Biomuta DOID:2394 / ovarian cancer [ cosmic, icgc ]
S171 C171 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S209 L209 Biomuta DOID:1725 / peritoneum cancer [ cosmic ]
S241 A241 Biomuta DOID:3571 / liver cancer [ cosmic ]
T257 M257 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]
T347 S347 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
S349 R349 Biomuta DOID:263 / kidney cancer [ cosmic ]