Protein Information

Cytoscape View


UniProt AC / UniProt ID Q96JK2 / DCAF5_HUMAN
Protein Name DDB1- and CUL4-associated factor 5
Gene Name Name: DCAF5
Synonyms:BCRG2,KIAA1824,WDR22;
Organism Homo sapiens (Human)

PRO ID PR:Q96JK2
DAG View
PRO Name DDB1- and CUL4-associated factor 5 (human)
Definition A DDB1- and CUL4-associated factor 5 that is encoded in the genome of human.
Short Label hDCAF5
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q96JK2 (DCAF5) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S10 Phosphorylation PhosphoSitePlus
K92 Ubiquitination PhosphoSitePlus
K209 Ubiquitination PhosphoSitePlus
Y260 Phosphorylation PhosphoSitePlus
S264 Phosphorylation PhosphoSitePlus
K364 Methylation PhosphoSitePlus
K364 Ubiquitination PhosphoSitePlus
C382 Methylation IEDB 31844290
S468 Phosphorylation PhosphoSitePlus
S476 Phosphorylation PhosphoSitePlus
S496 Phosphorylation PhosphoSitePlus
T497 Phosphorylation PhosphoSitePlus
T500 Phosphorylation PhosphoSitePlus
S552 Phosphorylation PhosphoSitePlus
S561 Phosphorylation PhosphoSitePlus
S562 Phosphorylation PhosphoSitePlus
S563 Phosphorylation PhosphoSitePlus
S564 Phosphorylation PhosphoSitePlus
S568 Phosphorylation PhosphoSitePlus
S580 Phosphorylation PhosphoSitePlus
T581 Phosphorylation PhosphoSitePlus
K604 Ubiquitination PhosphoSitePlus
Y615 Phosphorylation PhosphoSitePlus
S626 Phosphorylation PhosphoSitePlus
S628 Phosphorylation PhosphoSitePlus
T630 Phosphorylation PhosphoSitePlus
S631 Phosphorylation PhosphoSitePlus
S632 Phosphorylation PhosphoSitePlus
S638 Phosphorylation PhosphoSitePlus
S645 Phosphorylation PhosphoSitePlus   UniProt 24275569
S648 Phosphorylation PhosphoSitePlus   UniProt 23186163, 19690332, 24275569
S651 Phosphorylation PhosphoSitePlus   UniProt 19690332
S655 Phosphorylation PhosphoSitePlus
K665 Ubiquitination PhosphoSitePlus
K678 Ubiquitination PhosphoSitePlus
K699 Ubiquitination PhosphoSitePlus
K708 Ubiquitination PhosphoSitePlus
S794 Phosphorylation PhosphoSitePlus   UniProt 24275569
S860 Phosphorylation PhosphoSitePlus
S861 Phosphorylation PhosphoSitePlus
S865 Phosphorylation PhosphoSitePlus
T867 Phosphorylation PhosphoSitePlus
S917 Phosphorylation PhosphoSitePlus
K920 Acetylation PhosphoSitePlus
T929 Phosphorylation PhosphoSitePlus
S931 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S648 Phosphorylation HPRD 19664994, 18452278
S794 Phosphorylation HPRD 19664994


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K92 N92 Biomuta DOID:1324 / lung cancer [ cosmic ]
S264 F264 Biomuta DOID:4159 / skin cancer [ cosmic ]
K364 T364 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S468 F468 Biomuta DOID:4159 / skin cancer [ cosmic ]
S568 A568 Biomuta DOID:4362 / cervical cancer [ cosmic ]
S628 F628 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S631 L631 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ] DOID:4362 / cervical cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic, icgc ]
S651 Y651 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
K699 Q699 Biomuta DOID:1324 / lung cancer [ cosmic ]
K708 N708 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]
S865 L865 Biomuta DOID:10534 / stomach cancer [ cosmic ]
T867 A867 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
T867 I867 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
T929 K929 Biomuta DOID:2394 / ovarian cancer [ cosmic, icgc ]