iPTMnet Report for Q96JB3 (HIC2)
Protein Information
UniProt AC / UniProt ID | Q96JB3 / HIC2_HUMAN |
Protein Name | Hypermethylated in cancer 2 protein |
Gene Name | Name: HIC2 Synonyms:HRG22,KIAA1020,ZBTB30; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q96JB3 |
PRO Name | hypermethylated in cancer 2 protein (human) |
Definition | A hypermethylated in cancer 2 protein that is encoded in the genome of human. |
Short Label | hHIC2 |
Category | organism-gene |
Q96JB3 (HIC2) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S153 | Phosphorylation | score1 | PhosphoSitePlus | |||
S162 | Phosphorylation | score1 | PhosphoSitePlus | |||
S166 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
S169 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
S197 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
S253 | Phosphorylation | score1 | PhosphoSitePlus | |||
S280 | Phosphorylation | score1 | PhosphoSitePlus | |||
S348 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
S409 | Phosphorylation | score1 | PhosphoSitePlus | |||
S412 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
T612 | Phosphorylation | score1 | PhosphoSitePlus | |||
S613 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S197 | L197 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
T612 | A612 | Biomuta | DOID:1793 / pancreatic cancer [ cosmic ] | |
S613 | P613 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] | |
S613 | Y613 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] |