iPTMnet Report for Q96IY1 (NSL1)
Protein Information
UniProt AC / UniProt ID | Q96IY1 / NSL1_HUMAN |
Protein Name | Kinetochore-associated protein NSL1 homolog |
Gene Name | Name: NSL1 Synonyms:C1orf48;ORFNames:DC31,DC8,MIS14; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q96IY1 |
PRO Name | kinetochore-associated protein NSL1 homolog (human) |
Definition | A kinetochore-associated protein NSL1 that is encoded in the genome of human. |
Short Label | hNSL1 |
Category | organism-gene |
Q96IY1 (NSL1) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S4 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
S24 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 17525332 | ||
S29 | Phosphorylation | score1 | PhosphoSitePlus | |||
T31 | Phosphorylation | score1 | PhosphoSitePlus | |||
K59 | Ubiquitination | score1 | PhosphoSitePlus | |||
C102 | Methylation | score1 | IEDB | 31844290 | ||
K125 | Ubiquitination | score1 | PhosphoSitePlus | |||
K132 | Ubiquitination | score1 | PhosphoSitePlus | |||
K139 | Ubiquitination | score1 | PhosphoSitePlus | |||
K149 | Ubiquitination | score1 | PhosphoSitePlus | |||
K161 | Ubiquitination | score1 | PhosphoSitePlus | |||
K174 | Ubiquitination | score1 | PhosphoSitePlus | |||
K189 | Ubiquitination | score1 | PhosphoSitePlus | |||
T237 | Phosphorylation | score1 | PhosphoSitePlus | |||
T241 | Phosphorylation | score1 | PhosphoSitePlus | |||
T242 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 22067460, 18669648, 16565220 | ||
T244 | Phosphorylation | score2 | phospho.ELM UniProt | 18669648 | ||
T281 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S4 | F4 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, cosmic ] | |
K189 | T189 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] | |
T237 | K237 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
T244 | R244 | Biomuta | DOID:1612 / breast cancer [ cosmic, icgc ] |