Protein Information

Cytoscape View


UniProt AC / UniProt ID Q96IW7 / SC22A_HUMAN
Protein Name Vesicle-trafficking protein SEC22a
Gene Name Name: SEC22A
Synonyms:SEC22L2;
Organism Homo sapiens (Human)

PRO ID PR:Q96IW7
DAG View
PRO Name vesicle-trafficking protein SEC22a (human)
Definition A vesicle-trafficking protein SEC22a that is encoded in the genome of human.
Short Label hSEC22A
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q96IW7 (SEC22A) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S2 Acetylation UniProt 22814378
S2 Phosphorylation PhosphoSitePlus
S6 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648
S8 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648
Y36 Phosphorylation PhosphoSitePlus
K43 Ubiquitination PhosphoSitePlus
C51 Methylation IEDB 31844290
Y98 Phosphorylation PhosphoSitePlus
C111 Methylation IEDB 31844290
T134 Phosphorylation PhosphoSitePlus
K135 Ubiquitination PhosphoSitePlus
S139 Phosphorylation PhosphoSitePlus
T143 Phosphorylation PhosphoSitePlus
S154 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y98 * Biomuta DOID:1324 / lung cancer [ cosmic ]
K135 N135 Biomuta DOID:9256 / colorectal cancer [ cosmic ]