iPTMnet Report for Q96I34 (PPP1R16A)
Protein Information
UniProt AC / UniProt ID | Q96I34 / PP16A_HUMAN |
Protein Name | Protein phosphatase 1 regulatory subunit 16A precursor |
Gene Name | Name: PPP1R16A Synonyms:MYPT3; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q96I34 |
PRO Name | protein phosphatase 1 regulatory subunit 16A (human) |
Definition | A protein phosphatase 1 regulatory subunit 16A that is encoded in the genome of human. |
Short Label | hPPP1R16A |
Category | organism-gene |
Q96I34 (PPP1R16A) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S18 | Phosphorylation | score1 | PhosphoSitePlus | |||
S60 | Phosphorylation | score1 | PhosphoSitePlus | |||
T139 | O-Glycosylation | score1 | GlyGen | 29351928 | ||
T188 | Phosphorylation | score1 | IEDB | 35494241 | ||
S199 | Phosphorylation | score1 | PhosphoSitePlus | |||
S353 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 18220336 | ||
S418 | Phosphorylation | score1 | PhosphoSitePlus | |||
S433 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
Y434 | Phosphorylation | score1 | PhosphoSitePlus | |||
S437 | Phosphorylation | score1 | PhosphoSitePlus | |||
K451 | Acetylation | score1 | PhosphoSitePlus | |||
K460 | Acetylation | score1 | PhosphoSitePlus | |||
K460 | Ubiquitination | score1 | PhosphoSitePlus | |||
S478 | Phosphorylation | score1 | PhosphoSitePlus | |||
T511 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S18 | R18 | Biomuta | DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ] | |
T139 | M139 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ] | |
S418 | F418 | Biomuta | DOID:5041 / esophageal cancer [ cosmic, icgc ] | |
S437 | N437 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic, icgc ] |