iPTMnet Report for Q96HF1 (SFRP2)
Protein Information
UniProt AC / UniProt ID | Q96HF1 / SFRP2_HUMAN |
Protein Name | Secreted frizzled-related protein 2 precursor |
Gene Name | Name: SFRP2 Synonyms:FRP2,SARP1;ORFNames:FKSG12,UNQ361/PRO697; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q96HF1 |
PRO Name | secreted frizzled-related protein 2 (human) |
Definition | A secreted frizzled-related protein 2 that is encoded in the genome of human. |
Short Label | hSFRP2 |
Category | organism-gene |
Q96HF1 (SFRP2) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S7 | Phosphorylation | score1 | IEDB | 32387766 | ||
T220 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y222 | Phosphorylation | score1 | PhosphoSitePlus | |||
S235 | Phosphorylation | score1 | PhosphoSitePlus | |||
S289 | Phosphorylation | score2 | HPRD phospho.ELM PhosphoSitePlus | 17081983 |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S7 | L7 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
T220 | P220 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] | |
S235 | L235 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] DOID:2394 / ovarian cancer [ cosmic, icgc ] DOID:4159 / skin cancer [ cosmic, icgc ] DOID:11054 / urinary bladder cancer [ cosmic, icgc ] | |
S289 | N289 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] | |
S289 | I289 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] |