iPTMnet Report for Q96HF1 (SFRP2)
Protein Information
| UniProt AC / UniProt ID | Q96HF1 / SFRP2_HUMAN |
| Protein Name | Secreted frizzled-related protein 2 precursor |
| Gene Name | Name: SFRP2 Synonyms:FRP2,SARP1;ORFNames:FKSG12,UNQ361/PRO697; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q96HF1 |
| PRO Name | secreted frizzled-related protein 2 (human) |
| Definition | A secreted frizzled-related protein 2 that is encoded in the genome of human. |
| Short Label | hSFRP2 |
| Category | organism-gene |
Q96HF1 (SFRP2) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| S7 | Phosphorylation | score1 | IEDB | 32387766 | ||
| T220 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y222 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S235 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S289 | Phosphorylation | score2 | HPRD phospho.ELM PhosphoSitePlus | 17081983 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S7 | L7 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
| T220 | P220 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] | |
| S235 | L235 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] DOID:2394 / ovarian cancer [ cosmic, icgc ] DOID:4159 / skin cancer [ cosmic, icgc ] DOID:11054 / urinary bladder cancer [ cosmic, icgc ] | |
| S289 | N289 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] | |
| S289 | I289 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] |
DAG View