iPTMnet Report for Q96GW9 (MARS2)
Protein Information
| UniProt AC / UniProt ID | Q96GW9 / SYMM_HUMAN |
| Protein Name | Methionine--tRNA ligase, mitochondrial precursor |
| Gene Name | Name: MARS2 |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q96GW9 |
| PRO Name | methionine--tRNA ligase, mitochondrial (human) |
| Definition | A methionyl-tRNA synthetase, mitochondrial that is encoded in the genome of human. |
| Short Label | hMARS2 |
| Category | organism-gene |
DAG ViewQ96GW9 (MARS2) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| S16 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T90 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T92 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S131 | O-Glycosylation | score1 | GlyGen | 29351928 | ||
| T139 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T234 | Phosphorylation | score1 | PhosphoSitePlus | |||
| C361 | Methylation | score1 | IEDB | 31844290 | ||
| Y447 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S478 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y552 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| T92 | I92 | Biomuta | DOID:263 / kidney cancer [ cosmic ] | |
| S131 | P131 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
| C361 | * | Biomuta | DOID:5041 / esophageal cancer [ cosmic ] | |
| Y447 | * | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
| Y447 | N447 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] |
