iPTMnet Report for Q96FF9 (CDCA5)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q96FF9 / CDCA5_HUMAN
Protein Name Sororin
Gene Name Name: CDCA5
Organism Homo sapiens (Human)

PRO ID PR:Q96FF9
DAG View
PRO Name sororin (human)
Definition A sororin that is encoded in the genome of human.
Short Label hCDCA5
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q96FF9 (CDCA5) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S15 Phosphorylation PhosphoSitePlus
S21 Phosphorylation P06493 (CDK1) HPRD   IEDB   neXtProt   phospho.ELM   PRO   PhosphoSitePlus   RLIMS-P   UniProt 23186163, 26177583, 19664995, ...19691289, 27920218, 18669648, 21987589, 21878504, 20068231
T23 Phosphorylation PhosphoSitePlus
S29 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648
S33 Phosphorylation Q96GD4 (AURKB) , P06493 (CDK1) HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 23901111, ...20068231
S35 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19413330, 18669648, 20068231
S39 Phosphorylation PhosphoSitePlus
T48 Phosphorylation P06493 (CDK1) HPRD   phospho.ELM   PhosphoSitePlus 21878504, 16964243
S50 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 16964243
K61 Methylation PhosphoSitePlus
S75 Phosphorylation P06493 (CDK1) HPRD   phospho.ELM   PRO   PhosphoSitePlus   UniProt 23186163, 18212344, 18220336, ...18669648, 21987589, 21878504, 20068231, 17081983
S79 Phosphorylation P27361 (MAPK3) , P28482 (MAPK1) , P06493 (CDK1) , Q96GD4 (AURKB) HPRD   IEDB   neXtProt   phospho.ELM   PhosphoSitePlus   RLIMS-P   UniProt 23186163, 20551060, 33936100, ...23901111, 18669648, 21878504, 30784271, 20068231, 17081983
S83 Phosphorylation P06493 (CDK1) , Q96GD4 (AURKB) HPRD   phospho.ELM   PhosphoSitePlus   UniProt 23186163, 23901111, 18669648, ...22267324, 20068231
T98 Phosphorylation PhosphoSitePlus   UniProt 23186163
K99 Ubiquitination PhosphoSitePlus
K104 Ubiquitination PhosphoSitePlus
T105 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648, 20068231
S107 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 19690332, ...20068231
T111 Phosphorylation Q96GD4 (AURKB) , P06493 (CDK1) HPRD   phospho.ELM   PhosphoSitePlus   UniProt 23186163, 23901111, 18669648, ...21878504, 20068231
T113 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648, 20068231
S114 Phosphorylation HPRD 20068231
T115 Phosphorylation P06493 (CDK1) , Q96GD4 (AURKB) HPRD   phospho.ELM   PhosphoSitePlus   UniProt 21878504, 18669648, 23901111, ...20068231
S124 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648, 20068231
S125 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S126 Phosphorylation Q96GD4 (AURKB) , P06493 (CDK1) HPRD   PhosphoSitePlus 23901111, 20068231
S139 Phosphorylation Q96GD4 (AURKB) , P06493 (CDK1) PhosphoSitePlus 23901111
S145 Phosphorylation IEDB   PhosphoSitePlus 27920218
Y146 Phosphorylation PhosphoSitePlus
S147 Phosphorylation IEDB   PhosphoSitePlus 27920218
T151 Phosphorylation Q96GD4 (AURKB) , P06493 (CDK1) PhosphoSitePlus 23901111
S154 Phosphorylation PhosphoSitePlus   UniProt 23186163
T157 Phosphorylation PhosphoSitePlus
S158 Phosphorylation PhosphoSitePlus
T159 Phosphorylation P06493 (CDK1) , Q96GD4 (AURKB) neXtProt   phospho.ELM   PRO   PhosphoSitePlus   UniProt 23186163, 18220336, 23901111, ...21987589, 21878504
S164 Phosphorylation P06493 (CDK1) , Q96GD4 (AURKB) HPRD   PhosphoSitePlus 23901111, 20068231
S178 Phosphorylation HPRD   PhosphoSitePlus 20068231
S181 Phosphorylation P06493 (CDK1) PhosphoSitePlus 21878504
S186 Phosphorylation PhosphoSitePlus
K197 Ubiquitination PhosphoSitePlus
T204 Phosphorylation PhosphoSitePlus
S209 Phosphorylation P06493 (CDK1) , P28482 (MAPK1) , P27361 (MAPK3) HPRD   neXtProt   phospho.ELM   PhosphoSitePlus   RLIMS-P   UniProt 19413330, 21406692, 20551060, ...18669648, 21878504, 20068231


Proteoforms

PRO ID (Short Label) Sites PTM Enzyme Source PMID
PR:000046667 (hCDCA5/Phos:1) pS21,pS75,pT159 PRO


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S15 C15 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]
S29 F29 Biomuta DOID:4606 / bile duct cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic, icgc ]
S33 L33 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S33 * Biomuta DOID:1324 / lung cancer [ cosmic ]
T48 I48 Biomuta [ cosmic ]
S75 L75 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S124 F124 Biomuta DOID:11054 / urinary bladder cancer [ cosmic ]
S125 C125 Biomuta DOID:1324 / lung cancer [ cosmic ]
S126 F126 Biomuta DOID:4362 / cervical cancer [ cosmic, icgc ]
T151 I151 Biomuta DOID:1793 / pancreatic cancer [ icgc ]
S158 F158 Biomuta [ cosmic ] DOID:4159 / skin cancer [ cosmic, icgc ]
S164 F164 Biomuta DOID:4159 / skin cancer [ cosmic ]
S181 L181 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:2531 / hematologic cancer [ cosmic ]
S181 * Biomuta DOID:4159 / skin cancer [ cosmic ]