iPTMnet Report for Q96FC9 (DDX11)
Protein Information
UniProt AC / UniProt ID | Q96FC9 / DDX11_HUMAN |
Protein Name | ATP-dependent DNA helicase DDX11 |
Gene Name | Name: DDX11 Synonyms:CHL1,CHLR1; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q96FC9 |
PRO Name | ATP-dependent DNA helicase DDX11 (human) |
Definition | An ATP-dependent DNA helicase DDX11 that is encoded in the genome of human. |
Short Label | hDDX11 |
Category | organism-gene |
Q96FC9 (DDX11) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
K38 | Ubiquitination | score1 | PhosphoSitePlus | |||
K88 | Ubiquitination | score1 | PhosphoSitePlus | |||
T104 | Phosphorylation | score1 | PhosphoSitePlus | |||
K120 | Ubiquitination | score1 | PhosphoSitePlus | |||
K131 | Ubiquitination | score1 | PhosphoSitePlus | |||
K154 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y202 | Phosphorylation | score1 | PhosphoSitePlus | |||
S204 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 18669648 | ||
S237 | Phosphorylation | score1 | PhosphoSitePlus | |||
K247 | Ubiquitination | score1 | PhosphoSitePlus | |||
K253 | Ubiquitination | score1 | PhosphoSitePlus | |||
S262 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
K273 | Ubiquitination | score1 | PhosphoSitePlus | |||
K303 | Sumoylation | score1 | PhosphoSitePlus | |||
K311 | Ubiquitination | score1 | PhosphoSitePlus | |||
K335 | Ubiquitination | score1 | PhosphoSitePlus | |||
K345 | Ubiquitination | score1 | PhosphoSitePlus | |||
K460 | Ubiquitination | score1 | PhosphoSitePlus | |||
S467 | Phosphorylation | score1 | PhosphoSitePlus | |||
S469 | Phosphorylation | score1 | PhosphoSitePlus | |||
K501 | Ubiquitination | score1 | PhosphoSitePlus | |||
K507 | Ubiquitination | score1 | PhosphoSitePlus | |||
K526 | Ubiquitination | score1 | PhosphoSitePlus | |||
T541 | Phosphorylation | score1 | PhosphoSitePlus | |||
T542 | Phosphorylation | score1 | PhosphoSitePlus | |||
S589 | Phosphorylation | score1 | PhosphoSitePlus | |||
K596 | Ubiquitination | score1 | PhosphoSitePlus | |||
K611 | Ubiquitination | score1 | PhosphoSitePlus | |||
K722 | Ubiquitination | score1 | PhosphoSitePlus | |||
K733 | Ubiquitination | score1 | PhosphoSitePlus | |||
K734 | Ubiquitination | score1 | PhosphoSitePlus | |||
K740 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y752 | Phosphorylation | score1 | PhosphoSitePlus | |||
S753 | Phosphorylation | score1 | PhosphoSitePlus | |||
T818 | Phosphorylation | score1 | PhosphoSitePlus | |||
T825 | Phosphorylation | score1 | PhosphoSitePlus |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S204 | Phosphorylation | score0 | HPRD | 18669648 | ||
S274 | Phosphorylation | score0 | HPRD | 20068231 | ||
T541 | Phosphorylation | score0 | HPRD | 19651622 | ||
T542 | Phosphorylation | score0 | HPRD | 19651622 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
K811 | Ubiquitination | score1 | PhosphoSitePlus | |||
K830 | Ubiquitination | score1 | PhosphoSitePlus | |||
K839 | Ubiquitination | score1 | PhosphoSitePlus | |||
K853 | Ubiquitination | score1 | PhosphoSitePlus | |||
K873 | Ubiquitination | score1 | PhosphoSitePlus | |||
K897 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
K154 | R154 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
S204 | N204 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] | |
S237 | C237 | Biomuta | DOID:2394 / ovarian cancer [ cosmic, icgc ] | |
K253 | M253 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
K273 | R273 | Biomuta | DOID:3571 / liver cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ] DOID:1781 / thyroid gland cancer [ cosmic ] DOID:8618 / oral cavity cancer [ cosmic ] DOID:1319 / brain cancer [ cosmic ] DOID:11054 / urinary bladder cancer [ cosmic ] | |
T541 | M541 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
S753 | C753 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] DOID:363 / uterine cancer [ cosmic, icgc ] DOID:11054 / urinary bladder cancer [ cosmic, icgc ] |