iPTMnet Report for Q96EZ8 (MCRS1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q96EZ8 / MCRS1_HUMAN
Protein Name Microspherule protein 1
Gene Name Name: MCRS1
Synonyms:INO80Q,MSP58;
Organism Homo sapiens (Human)

PRO ID PR:Q96EZ8
DAG View
PRO Name microspherule protein 1 (human)
Definition A microspherule protein 1 that is encoded in the genome of human.
Short Label hMCRS1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q96EZ8 (MCRS1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
M1 Acetylation UniProt 22814378
S20 Phosphorylation PhosphoSitePlus
S22 Phosphorylation PhosphoSitePlus   UniProt 20068231
S27 Phosphorylation PhosphoSitePlus
K32 Acetylation PhosphoSitePlus
S35 Phosphorylation PhosphoSitePlus   RLIMS-P 27192185
S36 Phosphorylation PhosphoSitePlus   RLIMS-P 27192185
S48 Phosphorylation PhosphoSitePlus
K56 Sumoylation PhosphoSitePlus
S64 Phosphorylation RLIMS-P 30785839
S65 Phosphorylation RLIMS-P 30785839
K74 Methylation PhosphoSitePlus
S85 Phosphorylation PhosphoSitePlus
S98 Phosphorylation PhosphoSitePlus
S102 Phosphorylation PhosphoSitePlus
T103 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 16964243
S108 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 16964243, 18669648, ...19690332, 20068231
T116 Phosphorylation PhosphoSitePlus
K117 Ubiquitination PhosphoSitePlus
K123 Acetylation PhosphoSitePlus   UniProt 19608861
K130 Acetylation PhosphoSitePlus   UniProt 19608861
K130 Ubiquitination PhosphoSitePlus
K186 Methylation IEDB 32357974
K206 Ubiquitination PhosphoSitePlus
K211 Ubiquitination PhosphoSitePlus
K219 Ubiquitination PhosphoSitePlus
S282 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 23186163, 17081983, ...16565220, 18669648, 24275569, 19690332, 20068231
K292 Ubiquitination PhosphoSitePlus
K370 Ubiquitination PhosphoSitePlus
K397 Ubiquitination PhosphoSitePlus
K458 Ubiquitination PhosphoSitePlus
T460 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T18 Phosphorylation HPRD 20068231
S22 Phosphorylation HPRD 19007248, 20068231
S102 Phosphorylation HPRD 19413330, 19664995, 20068231
T103 Phosphorylation HPRD 19413330, 18669648, 16964243, ...20068231, 19664995
S108 Phosphorylation HPRD 19413330, 18669648, 16964243, ...20068231, 19664995
S282 Phosphorylation HPRD 19664994, 19664995, 16565220, ...19651622, 18669648, 18452278, 15345747, 20068231
Site PTM Type PTM Enzyme Score Source PMID
S14 Phosphorylation PhosphoSitePlus
S18 Phosphorylation PhosphoSitePlus
S24 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S18 Y18 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S24 L24 Biomuta DOID:4159 / skin cancer [ cosmic ]
S35 F35 Biomuta DOID:11054 / urinary bladder cancer [ cosmic ]
S48 F48 Biomuta DOID:4159 / skin cancer [ cosmic ]
T103 A103 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
K123 E123 Biomuta DOID:2021 / placenta cancer [ cosmic ]
K206 T206 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]