iPTMnet Report for Q96EZ8 (MCRS1)
Protein Information
UniProt AC / UniProt ID | Q96EZ8 / MCRS1_HUMAN |
Protein Name | Microspherule protein 1 |
Gene Name | Name: MCRS1 Synonyms:INO80Q,MSP58; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q96EZ8 |
PRO Name | microspherule protein 1 (human) |
Definition | A microspherule protein 1 that is encoded in the genome of human. |
Short Label | hMCRS1 |
Category | organism-gene |
Q96EZ8 (MCRS1) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
M1 | Acetylation | score1 | UniProt | 22814378 | ||
S20 | Phosphorylation | score1 | PhosphoSitePlus | |||
S22 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 20068231 | ||
S27 | Phosphorylation | score1 | PhosphoSitePlus | |||
K32 | Acetylation | score1 | PhosphoSitePlus | |||
S35 | Phosphorylation | score3 | PhosphoSitePlus RLIMS-P | 27192185 | ||
S36 | Phosphorylation | score3 | PhosphoSitePlus RLIMS-P | 27192185 | ||
S48 | Phosphorylation | score1 | PhosphoSitePlus | |||
K56 | Sumoylation | score1 | PhosphoSitePlus | |||
S64 | Phosphorylation | score0 | RLIMS-P | 30785839 | ||
S65 | Phosphorylation | score0 | RLIMS-P | 30785839 | ||
K74 | Methylation | score1 | PhosphoSitePlus | |||
S85 | Phosphorylation | score1 | PhosphoSitePlus | |||
S98 | Phosphorylation | score1 | PhosphoSitePlus | |||
S102 | Phosphorylation | score1 | PhosphoSitePlus | |||
T103 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 18669648, 16964243 | ||
S108 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 23186163, 16964243, 18669648, ... | ||
T116 | Phosphorylation | score1 | PhosphoSitePlus | |||
K117 | Ubiquitination | score1 | PhosphoSitePlus | |||
K123 | Acetylation | score2 | PhosphoSitePlus UniProt | 19608861 | ||
K130 | Acetylation | score2 | PhosphoSitePlus UniProt | 19608861 | ||
K130 | Ubiquitination | score1 | PhosphoSitePlus | |||
K186 | Methylation | score1 | IEDB | 32357974 | ||
K206 | Ubiquitination | score1 | PhosphoSitePlus | |||
K211 | Ubiquitination | score1 | PhosphoSitePlus | |||
K219 | Ubiquitination | score1 | PhosphoSitePlus | |||
S282 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 21406692, 23186163, 17081983, ... | ||
K292 | Ubiquitination | score1 | PhosphoSitePlus | |||
K370 | Ubiquitination | score1 | PhosphoSitePlus | |||
K397 | Ubiquitination | score1 | PhosphoSitePlus | |||
K458 | Ubiquitination | score1 | PhosphoSitePlus | |||
T460 | Phosphorylation | score1 | PhosphoSitePlus |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
T18 | Phosphorylation | score0 | HPRD | 20068231 | ||
S22 | Phosphorylation | score0 | HPRD | 19007248, 20068231 | ||
S102 | Phosphorylation | score0 | HPRD | 19413330, 19664995, 20068231 | ||
T103 | Phosphorylation | score0 | HPRD | 19413330, 18669648, 16964243, ... | ||
S108 | Phosphorylation | score0 | HPRD | 19413330, 18669648, 16964243, ... | ||
S282 | Phosphorylation | score0 | HPRD | 19664994, 19664995, 16565220, ... |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S14 | Phosphorylation | score1 | PhosphoSitePlus | |||
S18 | Phosphorylation | score1 | PhosphoSitePlus | |||
S24 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S18 | Y18 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
S24 | L24 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
S35 | F35 | Biomuta | DOID:11054 / urinary bladder cancer [ cosmic ] | |
S48 | F48 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
T103 | A103 | Biomuta | DOID:2531 / hematologic cancer [ cosmic ] | |
K123 | E123 | Biomuta | DOID:2021 / placenta cancer [ cosmic ] | |
K206 | T206 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] |