iPTMnet Report for Q96EP1 (CHFR)
Protein Information
| UniProt AC / UniProt ID | Q96EP1 / CHFR_HUMAN |
| Protein Name | E3 ubiquitin-protein ligase CHFR |
| Gene Name | Name: CHFR Synonyms:RNF196; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q96EP1 |
| PRO Name | E3 ubiquitin-protein ligase CHFR (human) |
| Definition | An E3 ubiquitin-protein ligase CHFR that is encoded in the genome of human. |
| Short Label | hCHFR |
| Category | organism-gene |
Q96EP1 (CHFR) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| S10 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T39 | Phosphorylation | score0 | RLIMS-P | 25578860 | ||
| T130 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S133 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S208 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S214 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S244 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
| K384 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K393 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T576 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S578 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S590 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y592 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K663 | Sumoylation | score1 | PhosphoSitePlus |
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| S122 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S133 | Y133 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| K384 | E384 | Biomuta | DOID:4159 / skin cancer [ cosmic ] |
DAG View