iPTMnet Report for Q96EL3 (MRPL53)
Protein Information
UniProt AC / UniProt ID | Q96EL3 / RM53_HUMAN |
Protein Name | Large ribosomal subunit protein mL53 precursor |
Gene Name | Name: MRPL53 |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q96EL3 |
PRO Name | 39S ribosomal protein L53, mitochondrial (human) |
Definition | A 39S ribosomal protein L53, mitochondrial that is encoded in the genome of human. |
Short Label | hMRPL53 |
Category | organism-gene |
Q96EL3 (MRPL53) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
C21 | S-Nitrosylation | score0 | dbSNO | 19483679 | ||
K41 | Ubiquitination | score1 | PhosphoSitePlus | |||
C49 | S-Nitrosylation | score0 | dbSNO | 26338901 | ||
C63 | S-Nitrosylation | score0 | dbSNO | 26338901 | ||
S92 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 20068231 | ||
T110 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 20068231 |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
C21 | S21 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] | |
K41 | R41 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
C49 | F49 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] | |
S92 | F92 | Biomuta | DOID:4159 / skin cancer [ cosmic ] DOID:2531 / hematologic cancer [ cosmic ] |