iPTMnet Report for Q96ED9 (HOOK2)
Protein Information
UniProt AC / UniProt ID | Q96ED9 / HOOK2_HUMAN |
Protein Name | Protein Hook homolog 2 |
Gene Name | Name: HOOK2 |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q96ED9 |
PRO Name | protein Hook homolog 2 (human) |
Definition | A protein Hook homolog 2 that is encoded in the genome of human. |
Short Label | hHOOK2 |
Category | organism-gene |
Q96ED9 (HOOK2) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S161 | Phosphorylation | score1 | PhosphoSitePlus | |||
S163 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 18669648 | ||
Y167 | Phosphorylation | score1 | PhosphoSitePlus | |||
S181 | Phosphorylation | score1 | PhosphoSitePlus | |||
K208 | Ubiquitination | score1 | PhosphoSitePlus | |||
S210 | Phosphorylation | score1 | PhosphoSitePlus | |||
T230 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
S316 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y397 | Phosphorylation | score1 | PhosphoSitePlus | |||
S437 | Phosphorylation | score1 | PhosphoSitePlus | |||
T571 | Phosphorylation | score1 | PhosphoSitePlus | |||
T613 | Phosphorylation | score1 | PhosphoSitePlus | |||
S630 | Phosphorylation | score1 | PhosphoSitePlus | |||
S665 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y668 | Phosphorylation | score1 | PhosphoSitePlus | |||
S689 | Phosphorylation | score1 | PhosphoSitePlus | |||
S710 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 24275569 |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S163 | * | Biomuta | DOID:1612 / breast cancer [ cosmic ] | |
T230 | P230 | Biomuta | DOID:2394 / ovarian cancer [ cosmic, icgc ] | |
T230 | N230 | Biomuta | DOID:2394 / ovarian cancer [ cosmic, icgc ] | |
S630 | F630 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
S630 | A630 | Biomuta | DOID:10283 / prostate cancer [ cosmic ] | |
S665 | I665 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] |