iPTMnet Report for Q96DX4 (RSPRY1)
Protein Information
UniProt AC / UniProt ID | Q96DX4 / RSPRY_HUMAN |
Protein Name | RING finger and SPRY domain-containing protein 1 precursor |
Gene Name | Name: RSPRY1 Synonyms:KIAA1972;ORFNames:UNQ328/PRO444; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q96DX4 |
PRO Name | RING finger and SPRY domain-containing protein 1 (human) |
Definition | A RING finger and SPRY domain-containing protein 1 that is encoded in the genome of human. |
Short Label | hRSPRY1 |
Category | organism-gene |
Q96DX4 (RSPRY1) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S55 | Phosphorylation | score1 | PhosphoSitePlus | |||
K97 | Ubiquitination | score1 | PhosphoSitePlus | |||
S144 | O-Glycosylation | score1 | GlyGen | 29351928 | ||
K177 | Ubiquitination | score1 | PhosphoSitePlus | |||
K260 | Ubiquitination | score1 | PhosphoSitePlus | |||
K286 | Ubiquitination | score1 | PhosphoSitePlus | |||
K312 | Ubiquitination | score1 | PhosphoSitePlus | |||
S316 | Phosphorylation | score1 | PhosphoSitePlus | |||
S317 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y330 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y397 | Phosphorylation | score1 | PhosphoSitePlus | |||
K415 | Ubiquitination | score1 | PhosphoSitePlus | |||
C421 | Methylation | score1 | IEDB | 31844290 | ||
S460 | Phosphorylation | score1 | PhosphoSitePlus | |||
K518 | Ubiquitination | score1 | PhosphoSitePlus | |||
S545 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S55 | N55 | Biomuta | DOID:1793 / pancreatic cancer [ cosmic ] | |
S144 | C144 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
Y330 | C330 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
K415 | R415 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
S460 | C460 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] | |
S545 | G545 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] |