iPTMnet Report for Q96C90 (PPP1R14B)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q96C90 / PP14B_HUMAN
Protein Name Protein phosphatase 1 regulatory subunit 14B
Gene Name Name: PPP1R14B
Synonyms:PLCB3N,PNG;
Organism Homo sapiens (Human)

PRO ID PR:Q96C90
DAG View
PRO Name protein phosphatase 1 regulatory subunit 14B (human)
Definition A protein phosphatase 1 regulatory subunit 14B that is encoded in the genome of human.
Short Label hPPP1R14B
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q96C90 (PPP1R14B) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 19413330, 22814378, 22223895
S4 Phosphorylation HPRD   PhosphoSitePlus 18491316
S21 Phosphorylation PhosphoSitePlus   UniProt 23186163
R27 Methylation PhosphoSitePlus
Y29 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 20068231
S32 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 23186163, 16964243, 18669648, ...19415658, 20068231
T57 Phosphorylation HPRD   IEDB   phospho.ELM   PhosphoSitePlus   RLIMS-P 35494241, 18212344, 12144526, ...12030846, 10606530, 16397254
T57 Phosphorylation O75116 (ROCK2) PhosphoSitePlus 12144526
T57 Phosphorylation P17252 (PRKCA) PhosphoSitePlus 10606530
T57 Phosphorylation Q05655 (PRKCD) PhosphoSitePlus 12144526
T57 Phosphorylation Q13418 (ILK) phospho.ELM   PhosphoSitePlus 12030846, 16397254, 12144526
K59 Acetylation PhosphoSitePlus
K59 Methylation PhosphoSitePlus
K114 Ubiquitination PhosphoSitePlus
C120 Methylation IEDB 31844290
Y121 Phosphorylation PhosphoSitePlus
K122 Ubiquitination PhosphoSitePlus
S142 Phosphorylation PhosphoSitePlus
T143 Phosphorylation HPRD   PhosphoSitePlus 20068231
K146 Acetylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y29 N29 Biomuta DOID:263 / kidney cancer [ cosmic, icgc ]
Y121 H121 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ]
T143 I143 Biomuta DOID:3571 / liver cancer [ cosmic ]