iPTMnet Report for Q96C24 (SYTL4)
Protein Information
UniProt AC / UniProt ID | Q96C24 / SYTL4_HUMAN |
Protein Name | Synaptotagmin-like protein 4 |
Gene Name | Name: SYTL4 |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q96C24 |
PRO Name | synaptotagmin-like protein 4 (human) |
Definition | A synaptotagmin-like protein 4 that is encoded in the genome of human. |
Short Label | hSYTL4 |
Category | organism-gene |
Q96C24 (SYTL4) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
K47 | Ubiquitination | score1 | PhosphoSitePlus | |||
S74 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 18088087 | ||
K123 | Ubiquitination | score1 | PhosphoSitePlus | |||
R130 | Methylation | score1 | PhosphoSitePlus | |||
S133 | Phosphorylation | score1 | PhosphoSitePlus | |||
R137 | Methylation | score1 | PhosphoSitePlus | |||
K177 | Ubiquitination | score1 | PhosphoSitePlus | |||
S180 | Phosphorylation | score1 | PhosphoSitePlus | |||
S199 | Phosphorylation | score1 | phospho.ELM | 18669648 | ||
S201 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 18669648, 18088087 | ||
S204 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 18669648, 18088087 | ||
T206 | Phosphorylation | score1 | PhosphoSitePlus | |||
S213 | Phosphorylation | score1 | PhosphoSitePlus | |||
S217 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 18669648, 23186163 | ||
K220 | Ubiquitination | score1 | PhosphoSitePlus | |||
S221 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
S231 | Phosphorylation | score1 | PhosphoSitePlus | |||
S269 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y271 | Phosphorylation | score1 | PhosphoSitePlus | |||
S274 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 24275569 | ||
S289 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 18088087, 18669648, 23186163 | ||
S294 | Phosphorylation | score1 | PhosphoSitePlus | |||
S296 | Phosphorylation | score1 | PhosphoSitePlus | |||
S340 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y345 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y366 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y396 | Phosphorylation | score1 | PhosphoSitePlus | |||
S488 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 18088087, 23186163 | ||
K510 | Ubiquitination | score1 | PhosphoSitePlus | |||
T511 | Phosphorylation | score1 | PhosphoSitePlus | |||
S520 | Phosphorylation | score1 | PhosphoSitePlus | |||
T546 | Phosphorylation | score1 | PhosphoSitePlus | |||
S547 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y554 | Phosphorylation | score1 | PhosphoSitePlus | |||
S563 | Phosphorylation | score1 | PhosphoSitePlus | |||
T567 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y649 | Phosphorylation | score1 | PhosphoSitePlus | |||
S652 | Phosphorylation | score1 | PhosphoSitePlus | |||
K666 | Acetylation | score1 | PhosphoSitePlus | |||
K668 | Acetylation | score1 | PhosphoSitePlus |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S74 | Phosphorylation | score0 | HPRD | 18088087 | ||
S199 | Phosphorylation | score0 | HPRD | 18669648 | ||
S201 | Phosphorylation | score0 | HPRD | 18669648, 18088087, 18452278 | ||
S204 | Phosphorylation | score0 | HPRD | 18669648, 18088087, 18452278 | ||
S217 | Phosphorylation | score0 | HPRD | 18669648 | ||
S289 | Phosphorylation | score0 | HPRD | 18669648, 18088087 | ||
S488 | Phosphorylation | score0 | HPRD | 18088087 |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
R130 | S130 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] DOID:1324 / lung cancer [ cosmic, icgc ] | |
R130 | C130 | Biomuta | [ cosmic ] | |
R137 | G137 | Biomuta | DOID:1612 / breast cancer [ cosmic, icgc ] | |
R137 | S137 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
K177 | N177 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
S180 | N180 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
S213 | C213 | Biomuta | DOID:4362 / cervical cancer [ cosmic, icgc ] | |
S231 | F231 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
S289 | F289 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
S340 | N340 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
S520 | N520 | Biomuta | DOID:1319 / brain cancer [ cosmic, icgc ] | |
Y649 | * | Biomuta | DOID:1324 / lung cancer [ cosmic ] |