iPTMnet Report for Q96BD8 (SKA1)
Protein Information
UniProt AC / UniProt ID | Q96BD8 / SKA1_HUMAN |
Protein Name | Spindle and kinetochore-associated protein 1 |
Gene Name | Name: SKA1 Synonyms:C18orf24; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q96BD8 |
PRO Name | spindle and kinetochore-associated protein 1 (human) |
Definition | A spindle and kinetochore-associated protein 1 that is encoded in the genome of human. |
Short Label | hSKA1 |
Category | organism-gene |
Q96BD8 (SKA1) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
A2 | Acetylation | score1 | UniProt | 19413330 | ||
S4 | Phosphorylation | score1 | PhosphoSitePlus | |||
S11 | Phosphorylation | score1 | PhosphoSitePlus | |||
S25 | Phosphorylation | score1 | PhosphoSitePlus | |||
K36 | Ubiquitination | score1 | PhosphoSitePlus | |||
S76 | Phosphorylation | score1 | PhosphoSitePlus | |||
K117 | Sumoylation | score1 | PhosphoSitePlus | |||
K117 | Ubiquitination | score1 | PhosphoSitePlus | |||
K135 | Ubiquitination | score1 | PhosphoSitePlus | |||
C142 | Methylation | score1 | IEDB | 31844290 | ||
K153 | Ubiquitination | score1 | PhosphoSitePlus | |||
T157 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y158 | Phosphorylation | score1 | PhosphoSitePlus | |||
K166 | Ubiquitination | score1 | PhosphoSitePlus | |||
K170 | Ubiquitination | score1 | PhosphoSitePlus | |||
K175 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y176 | Phosphorylation | score1 | PhosphoSitePlus | |||
K177 | Ubiquitination | score1 | PhosphoSitePlus | |||
K183 | Ubiquitination | score1 | PhosphoSitePlus | |||
K184 | Ubiquitination | score1 | PhosphoSitePlus | |||
K203 | Ubiquitination | score1 | PhosphoSitePlus | |||
K206 | Ubiquitination | score1 | PhosphoSitePlus | |||
R245 | Methylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
A2 | T2 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
S11 | C11 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
T157 | I157 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
R245 | Q245 | Biomuta | DOID:1612 / breast cancer [ cosmic, icgc ] |