iPTMnet Report for Q96AB3 (ISOC2)
Protein Information
UniProt AC / UniProt ID | Q96AB3 / ISOC2_HUMAN |
Protein Name | Isochorismatase domain-containing protein 2 |
Gene Name | Name: ISOC2 |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q96AB3 |
PRO Name | isochorismatase domain-containing protein 2 (human) |
Definition | An isochorismatase domain-containing protein 2 that is encoded in the genome of human. |
Short Label | hISOC2 |
Category | organism-gene |
Q96AB3 (ISOC2) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S7 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 18691976 | ||
C21 | S-Nitrosylation | score0 | dbSNO | 25040305 | ||
K26 | Acetylation | score1 | PhosphoSitePlus | |||
K26 | Ubiquitination | score1 | PhosphoSitePlus | |||
C107 | S-Nitrosylation | score0 | dbSNO | 25040305 | ||
C114 | S-Nitrosylation | score0 | dbSNO | 25040305 | ||
R144 | Methylation | score1 | PhosphoSitePlus | |||
K178 | Acetylation | score1 | PhosphoSitePlus | |||
K182 | Acetylation | score1 | PhosphoSitePlus | |||
K185 | Acetylation | score1 | PhosphoSitePlus | |||
K185 | Ubiquitination | score1 | PhosphoSitePlus | |||
S191 | Phosphorylation | score1 | PhosphoSitePlus | |||
S202 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 24275569 |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
C114 | Y114 | Biomuta | DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ] |