iPTMnet Report for Q96A49 (SYAP1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q96A49 / SYAP1_HUMAN
Protein Name Synapse-associated protein 1
Gene Name Name: SYAP1
ORFNames:PRO3113;
Organism Homo sapiens (Human)

PRO ID PR:Q96A49
DAG View
PRO Name synapse-associated protein 1 (human)
Definition A synapse-associated protein 1 that is encoded in the genome of human.
Short Label hSYAP1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q96A49 (SYAP1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y60 Phosphorylation PhosphoSitePlus
S66 Phosphorylation PhosphoSitePlus
K70 Acetylation PhosphoSitePlus
K71 Acetylation PhosphoSitePlus
K71 Ubiquitination PhosphoSitePlus
T73 O-Glycosylation GlyGen   PhosphoSitePlus 23584533
T73 Phosphorylation PhosphoSitePlus
S75 Phosphorylation PhosphoSitePlus
T79 O-Glycosylation GlyGen   PhosphoSitePlus 23584533
T82 O-Glycosylation GlyGen   PhosphoSitePlus 23584533
S86 Phosphorylation PhosphoSitePlus
K91 Ubiquitination PhosphoSitePlus
K98 Ubiquitination PhosphoSitePlus
K106 Ubiquitination PhosphoSitePlus
K110 Acetylation PhosphoSitePlus
K110 Ubiquitination PhosphoSitePlus
T117 Phosphorylation HPRD   PhosphoSitePlus 20068231
K119 Ubiquitination PhosphoSitePlus
K147 Ubiquitination PhosphoSitePlus
K191 Acetylation PhosphoSitePlus
K194 Ubiquitination PhosphoSitePlus
K210 Ubiquitination PhosphoSitePlus
K227 Ubiquitination PhosphoSitePlus
S231 Phosphorylation PhosphoSitePlus
T248 Phosphorylation HPRD   IEDB   phospho.ELM   PhosphoSitePlus   UniProt 19413330, 21406692, 17287340, ...16964243, 15302935, 19007248, 32157095, 18669648, 24275569, 23186163, 18088087, 31848261, 20068231, 17081983
S267 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648
T268 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648, 17081983
S269 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648, 18491316, 17081983, ...18452278
S273 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648
K292 Ubiquitination PhosphoSitePlus
K301 Ubiquitination PhosphoSitePlus
K302 Ubiquitination PhosphoSitePlus
S313 Phosphorylation HPRD   PhosphoSitePlus   UniProt 19651622, 23186163, 20068231
Y327 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 17287340, 18452278
T331 Phosphorylation HPRD   PhosphoSitePlus 18452278
K335 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S86 F86 Biomuta DOID:363 / uterine cancer [ icgc ] DOID:4159 / skin cancer [ cosmic ]
K98 N98 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
K191 Q191 Biomuta DOID:3953 / adrenal gland cancer [ cosmic ]
S267 Y267 Biomuta DOID:363 / uterine cancer [ icgc ]
T268 I268 Biomuta DOID:4159 / skin cancer [ cosmic, icgc, tcga ]