Protein Information

Cytoscape View


UniProt AC / UniProt ID Q969T7 / 5NT3B_HUMAN
Protein Name 7-methylguanosine phosphate-specific 5'-nucleotidase
Gene Name Name: NT5C3B
Synonyms:NT5C3L;
Organism Homo sapiens (Human)

PRO ID PR:Q969T7
DAG View
PRO Name 7-methylguanosine phosphate-specific 5'-nucleotidase (human)
Definition A 7-methylguanosine phosphate-specific 5'-nucleotidase that is encoded in the genome of human.
Short Label hNT5C3B
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q969T7 (NT5C3B) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K10 Methylation PhosphoSitePlus
Y60 Phosphorylation PhosphoSitePlus
T78 Phosphorylation IEDB   PhosphoSitePlus 35494241
Y84 Phosphorylation PhosphoSitePlus
Y85 Phosphorylation PhosphoSitePlus
T94 Phosphorylation PhosphoSitePlus
K117 Ubiquitination PhosphoSitePlus
K256 Acetylation PhosphoSitePlus   UniProt 19608861
K256 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T94 I94 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K117 N117 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K256 R256 Biomuta DOID:10283 / prostate cancer [ cosmic, icgc ]