iPTMnet Report for Q969T4 (UBE2E3)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q969T4 / UB2E3_HUMAN
Protein Name Ubiquitin-conjugating enzyme E2 E3
Gene Name Name: UBE2E3
Synonyms:UBCE4,UBCH9;
Organism Homo sapiens (Human)

PRO ID PR:Q969T4
DAG View
PRO Name ubiquitin-conjugating enzyme E2 E3 (human)
Definition A ubiquitin-conjugating enzyme E2 E3 that is encoded in the genome of human.
Short Label hUBE2E3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q969T4 (UBE2E3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S2 Acetylation UniProt 19413330
S3 Phosphorylation HPRD   PhosphoSitePlus 19413330
S8 Phosphorylation HPRD   PhosphoSitePlus   UniProt 24275569, 20068231
S12 Phosphorylation phospho.ELM   PhosphoSitePlus 15302935
S19 Phosphorylation PhosphoSitePlus
K39 Ubiquitination PhosphoSitePlus
K50 Acetylation PhosphoSitePlus
K58 Acetylation PhosphoSitePlus
K58 Ubiquitination PhosphoSitePlus
K68 Ubiquitination PhosphoSitePlus
Y91 Phosphorylation PhosphoSitePlus
K150 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S2 F2 Biomuta DOID:1793 / pancreatic cancer [ icgc ]
S19 C19 Biomuta DOID:4159 / skin cancer [ cosmic ]
K50 T50 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]