iPTMnet Report for Q969S2 (NEIL2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q969S2 / NEIL2_HUMAN
Protein Name Endonuclease 8-like 2
Gene Name Name: NEIL2
Organism Homo sapiens (Human)

PRO ID PR:Q969S2
DAG View
PRO Name endonuclease 8-like 2 (human)
Definition An endonuclease 8-like 2 that is encoded in the genome of human.
Short Label hNEIL2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q969S2 (NEIL2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K50 Acetylation PhosphoSitePlus   UniProt 15175427
S68 Phosphorylation PhosphoSitePlus   UniProt 23186163
T70 Phosphorylation PhosphoSitePlus
K96 Ubiquitination PhosphoSitePlus
K154 Acetylation PhosphoSitePlus   UniProt 15175427
K234 Ubiquitination PhosphoSitePlus
K288 Ubiquitination PhosphoSitePlus
K299 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
K50 Acetylation PR:000007102 (EP300) PRO 15175427
K154 Acetylation PR:000007102 (EP300) PRO 15175427


Proteoforms

PRO ID (Short Label) Sites PTM Enzyme Source PMID
PR:000028592 (hNEIL2/iso:1/InitMet-/Ac:1) acK50,acK154 PR:000007102 (EP300) PRO 15175427


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K50 N50 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
T70 I70 Biomuta DOID:263 / kidney cancer [ cosmic ]
K288 N288 Biomuta DOID:4159 / skin cancer [ cosmic ]
K299 T299 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]