iPTMnet Report for Q969F2 (NKD2)
Protein Information
UniProt AC / UniProt ID | Q969F2 / NKD2_HUMAN |
Protein Name | Protein naked cuticle homolog 2 |
Gene Name | Name: NKD2 |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q969F2 |
PRO Name | protein naked cuticle homolog 2 (human) |
Definition | A protein naked cuticle homolog 2 that is encoded in the genome of human. |
Short Label | hNKD2 |
Category | organism-gene |
Q969F2 (NKD2) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
G2 | Myristoylation | score2 | UniProt | 15064403 | ||
S18 | Phosphorylation | score1 | PhosphoSitePlus | |||
S23 | Phosphorylation | score1 | PhosphoSitePlus | |||
S31 | Phosphorylation | score1 | PhosphoSitePlus | |||
K74 | Ubiquitination | score1 | PhosphoSitePlus | |||
S176 | Phosphorylation | score1 | PhosphoSitePlus | |||
S216 | Phosphorylation | score1 | PhosphoSitePlus | |||
S223 | Phosphorylation | score1 | PhosphoSitePlus | |||
T224 | Phosphorylation | score1 | PhosphoSitePlus | |||
S230 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y247 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y256 | Phosphorylation | score1 | PhosphoSitePlus | |||
T257 | Phosphorylation | score1 | PhosphoSitePlus | |||
S264 | Phosphorylation | score1 | PhosphoSitePlus | |||
S286 | Phosphorylation | score1 | PhosphoSitePlus | |||
S299 | Phosphorylation | score1 | PhosphoSitePlus | |||
S333 | Phosphorylation | score1 | PhosphoSitePlus | |||
S394 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y423 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S176 | N176 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] | |
S223 | T223 | Biomuta | DOID:2394 / ovarian cancer [ cosmic, icgc ] | |
T224 | S224 | Biomuta | DOID:3571 / liver cancer [ cosmic, icgc ] | |
S230 | L230 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] | |
T257 | K257 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
S333 | F333 | Biomuta | DOID:4159 / skin cancer [ cosmic ] DOID:8618 / oral cavity cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic, icgc ] |