Protein Information

Cytoscape View


UniProt AC / UniProt ID Q969F1 / TF3C6_HUMAN
Protein Name General transcription factor 3C polypeptide 6
Gene Name Name: GTF3C6
Synonyms:C6orf51;ORFNames:CDA020,NPD020;
Organism Homo sapiens (Human)

PRO ID PR:Q969F1
DAG View
PRO Name general transcription factor 3C polypeptide 6 (human)
Definition A general transcription factor 3C polypeptide 6 that is encoded in the genome of human.
Short Label hGTF3C6
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q969F1 (GTF3C6) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 21406692
S9 Phosphorylation PhosphoSitePlus   UniProt 21406692
S59 Phosphorylation PhosphoSitePlus
S104 Phosphorylation PhosphoSitePlus
K113 Acetylation PhosphoSitePlus
K113 Sumoylation PhosphoSitePlus
K114 Ubiquitination PhosphoSitePlus
K129 Ubiquitination PhosphoSitePlus
S160 Phosphorylation PhosphoSitePlus
S177 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
A2 E2 Biomuta DOID:3571 / liver cancer [ cosmic ]
K113 R113 Biomuta DOID:1324 / lung cancer [ cosmic ]
K113 N113 Biomuta DOID:363 / uterine cancer [ icgc ]
K129 N129 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S160 Y160 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
S160 C160 Biomuta DOID:3571 / liver cancer [ cosmic ]