iPTMnet Report for Q92945 (KHSRP)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q92945 / FUBP2_HUMAN
Protein Name Far upstream element-binding protein 2
Gene Name Name: KHSRP
Synonyms:FUBP2;
Organism Homo sapiens (Human)

PRO ID PR:Q92945
DAG View
PRO Name far upstream element-binding protein 2 (human)
Definition A far upstream element-binding protein 2 that is encoded in the genome of human.
Short Label hKHSRP
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q92945 (KHSRP) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S2 Acetylation UniProt 19413330, 22814378, 22223895
S2 Phosphorylation PhosphoSitePlus
T6 Phosphorylation PhosphoSitePlus
S54 O-Glycosylation GlyGen 23301498, 30444036, 35138101, ...30620550, 31492838, 32870666, 35289036, 35254053, 16408927, 30397120, 28657654, 32119511, 31637018, 32574038, 35132862, 22121020, 31373491, 27655845, 33214551, 30059200, 21740066, 29351928, 34019948, 35083852, 28510447
S54 Phosphorylation PhosphoSitePlus
S59 O-Glycosylation GlyGen 23301498, 30444036, 35138101, ...30620550, 31492838, 32870666, 35289036, 35254053, 16408927, 30397120, 28657654, 32119511, 31637018, 32574038, 35132862, 22121020, 31373491, 27655845, 33214551, 30059200, 21740066, 29351928, 34019948, 35083852, 28510447
K71 Methylation PhosphoSitePlus
K71 Ubiquitination PhosphoSitePlus
K87 Acetylation PhosphoSitePlus
K87 Ubiquitination PhosphoSitePlus
T94 O-Glycosylation GlyGen 23301498, 30444036, 35138101, ...30620550, 31492838, 32870666, 35289036, 35254053, 16408927, 30397120, 28657654, 32119511, 31637018, 32574038, 35132862, 22121020, 31373491, 27655845, 33214551, 30059200, 21740066, 29351928, 34019948, 35083852, 28510447
T94 Phosphorylation PhosphoSitePlus
T95 O-Glycosylation GlyGen 23301498, 30444036, 35138101, ...30620550, 31492838, 32870666, 35289036, 29351928, 16408927, 30397120, 28657654, 32119511, 31637018, 32574038, 32938750, 35132862, 22121020, 31373491, 27655845, 34846842, 33214551, 30059200, 21740066, 35254053, 34019948, 35083852, 28510447
T95 Phosphorylation phospho.ELM   PhosphoSitePlus 15302935
S99 O-Glycosylation GlyGen 23301498, 30444036, 35138101, ...30620550, 31492838, 32870666, 35289036, 35254053, 16408927, 30397120, 28657654, 32119511, 31637018, 32574038, 35132862, 22121020, 31373491, 27655845, 33214551, 30059200, 21740066, 29351928, 34019948, 35083852, 28510447
S99 Phosphorylation PhosphoSitePlus   UniProt 23186163
T100 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19413330, 18669648, 17287340, ...20068231
K109 Acetylation PhosphoSitePlus
K109 Methylation PhosphoSitePlus
K109 Ubiquitination PhosphoSitePlus
S120 Phosphorylation PhosphoSitePlus
K121 Acetylation PhosphoSitePlus
K121 Sumoylation PhosphoSitePlus
K121 Ubiquitination PhosphoSitePlus
K122 Acetylation PhosphoSitePlus
K122 Ubiquitination PhosphoSitePlus
S125 Phosphorylation PhosphoSitePlus   UniProt 23186163
S129 Phosphorylation PhosphoSitePlus   UniProt 23186163
S131 Phosphorylation PhosphoSitePlus   UniProt 23186163
S132 Phosphorylation Q13315 (ATM) HPRD   neXtProt   phospho.ELM   PhosphoSitePlus 17525332, 21329876
S144 O-Glycosylation GlyGen 23301498, 30444036, 35138101, ...30620550, 31492838, 32870666, 35289036, 35254053, 16408927, 30397120, 28657654, 32119511, 31637018, 32574038, 35132862, 22121020, 31373491, 27655845, 33214551, 30059200, 21740066, 29351928, 34019948, 35083852, 28510447
S144 Phosphorylation PhosphoSitePlus
Y149 Phosphorylation PhosphoSitePlus
R162 Methylation PhosphoSitePlus
K169 Ubiquitination PhosphoSitePlus
S174 Phosphorylation HPRD   PhosphoSitePlus 20068231
C176 Methylation IEDB 31844290
C176 S-Nitrosylation dbSNO 19483679, 26338901, 20140087
K177 Ubiquitination PhosphoSitePlus
S181 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19413330, 21406692, 23186163, ...16964243, 18691976, 18767875, 20058876, 19664995, 18452278, 17322306, 15302935, 18669648, 19690332, 19651622, 19369195, 19415658, 20068231, 17081983
S184 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19413330, 18669648, 23186163, ...20068231
S191 O-Glycosylation GlyGen 23301498, 30444036, 35138101, ...30620550, 31492838, 32870666, 35289036, 29351928, 16408927, 30397120, 28657654, 32119511, 31637018, 32574038, 32938750, 35132862, 22121020, 31373491, 27655845, 33214551, 30059200, 21740066, 35254053, 34019948, 35083852, 28510447
S191 Phosphorylation HPRD   PhosphoSitePlus 19413330
S193 Phosphorylation P31749 (AKT1) , P31751 (AKT2) neXtProt   PRO   PhosphoSitePlus   RLIMS-P   Signor   UniProt 23186163, 19198587, 17177604
T195 Phosphorylation PhosphoSitePlus
S200 Phosphorylation PhosphoSitePlus
K203 Ubiquitination PhosphoSitePlus
K205 Ubiquitination PhosphoSitePlus
T234 Phosphorylation PhosphoSitePlus
K251 Ubiquitination PhosphoSitePlus
T255 Phosphorylation PhosphoSitePlus
K257 Ubiquitination PhosphoSitePlus
K266 Acetylation PhosphoSitePlus
S274 Phosphorylation Q13315 (ATM) HPRD   neXtProt   phospho.ELM   PhosphoSitePlus   Signor   UniProt 17525332, 23186163, 21406692, ...18669648, 21329876, 20068231
T277 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648, 20068231
K281 Ubiquitination PhosphoSitePlus
R314 Methylation PhosphoSitePlus
Y317 Phosphorylation P12931 (SRC) PhosphoSitePlus 18698806
S319 Phosphorylation PhosphoSitePlus
S333 Phosphorylation PhosphoSitePlus
R340 Methylation PhosphoSitePlus
S341 Phosphorylation PhosphoSitePlus
K347 Ubiquitination PhosphoSitePlus
R355 Methylation PhosphoSitePlus
K359 Sumoylation PhosphoSitePlus
K359 Ubiquitination PhosphoSitePlus
R378 Methylation PhosphoSitePlus
R394 Methylation PhosphoSitePlus
S395 Phosphorylation PhosphoSitePlus   RLIMS-P 35240233
R411 Methylation PhosphoSitePlus   UniProt 24129315
R413 Methylation PhosphoSitePlus   UniProt 24129315
R415 Methylation PhosphoSitePlus   UniProt 24129315
C436 Methylation IEDB 31844290
C436 S-Nitrosylation dbSNO 20140087
R442 Methylation PhosphoSitePlus   UniProt 24129315
K448 Methylation PhosphoSitePlus
K448 Ubiquitination PhosphoSitePlus
S461 Phosphorylation PhosphoSitePlus
R478 Methylation PhosphoSitePlus
S480 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 21406692, 23186163, 17081983, ...18767875, 19651622, 18669648, 20068231
K488 Acetylation PhosphoSitePlus
K488 Ubiquitination PhosphoSitePlus
Y583 Phosphorylation P12931 (SRC) PhosphoSitePlus 18698806
Y625 Phosphorylation PhosphoSitePlus
Y626 Phosphorylation PhosphoSitePlus
K627 Acetylation PhosphoSitePlus
K628 Ubiquitination PhosphoSitePlus
Y644 Phosphorylation PhosphoSitePlus
K646 Ubiquitination PhosphoSitePlus
Y651 Phosphorylation PhosphoSitePlus
Y652 Phosphorylation PhosphoSitePlus
K653 Acetylation PhosphoSitePlus
K654 Ubiquitination PhosphoSitePlus
S670 O-Glycosylation GlyGen 23301498, 30444036, 35138101, ...30620550, 31492838, 32870666, 35289036, 35254053, 16408927, 30397120, 28657654, 32119511, 31637018, 32574038, 35132862, 22121020, 31373491, 27655845, 33214551, 30059200, 21740066, 29351928, 34019948, 35083852, 28510447
S670 Phosphorylation Q13315 (ATM) HPRD   neXtProt   phospho.ELM   PhosphoSitePlus   Signor 17525332, 21329876
Y674 Phosphorylation PhosphoSitePlus
Y681 Phosphorylation PhosphoSitePlus
Y688 Phosphorylation P12931 (SRC) PhosphoSitePlus 18698806
T692 Phosphorylation Q15759 (MAPK11) , Q16539 (MAPK14) neXtProt   PRO   PhosphoSitePlus   RLIMS-P 25352548, 16364914


Proteoforms

PRO ID (Short Label) Sites PTM Enzyme Source PMID
PR:000048104 (hKHSRP/InitMet-/Phos:1) pS193 PRO
PR:000048105 (hKHSRP/InitMet-/Phos:2) pT692 PRO


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S59 F59 Biomuta DOID:4159 / skin cancer [ cosmic ]
T94 M94 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
K109 R109 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
K109 N109 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
Y149 C149 Biomuta DOID:1319 / brain cancer [ icgc ]
C176 F176 Biomuta DOID:4362 / cervical cancer [ cosmic, icgc ]
S193 C193 Biomuta DOID:1324 / lung cancer [ cosmic ]
T277 M277 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
T277 A277 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
R314 W314 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
R314 Q314 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
S319 C319 Biomuta DOID:4362 / cervical cancer [ cosmic, icgc ]
S319 Y319 Biomuta DOID:3571 / liver cancer [ cosmic ]
R355 W355 Biomuta DOID:363 / uterine cancer [ icgc ] DOID:10534 / stomach cancer [ cosmic, icgc ]
R355 Q355 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
R411 * Biomuta DOID:9256 / colorectal cancer [ cosmic ]
R413 G413 Biomuta [ cosmic ]
R415 T415 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
R415 K415 Biomuta DOID:5041 / esophageal cancer [ cosmic ]
K448 I448 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]
S461 F461 Biomuta DOID:4159 / skin cancer [ cosmic ]
R478 L478 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
R478 W478 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
Y644 * Biomuta DOID:5041 / esophageal cancer [ cosmic ]
K654 M654 Biomuta DOID:5041 / esophageal cancer [ cosmic ]