iPTMnet Report for Q92934 (BAD)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q92934 / BAD_HUMAN
Protein Name Bcl2-associated agonist of cell death
Gene Name Name: BAD
Synonyms:BBC6,BCL2L8;
Organism Homo sapiens (Human)

PRO ID PR:Q92934
DAG View
PRO Name Bcl2-associated agonist of cell death (human)
Definition A Bcl2-associated agonist of cell death that is encoded in the genome of human.
Short Label hBAD
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q92934 (BAD) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
M1 Acetylation UniProt 22814378
S25 Phosphorylation HPRD   PhosphoSitePlus   UniProt 19413330, 23186163, 20068231
S32 Phosphorylation PhosphoSitePlus
S34 Phosphorylation PhosphoSitePlus
K36 Acetylation PhosphoSitePlus
S71 Phosphorylation PhosphoSitePlus
S74 Phosphorylation HPRD   neXtProt   PhosphoSitePlus   Signor 22096607, 20068231, 18452278
S74 Phosphorylation Q13153 (PAK1) neXtProt   PhosphoSitePlus   Signor 22096607
S75 Phosphorylation HPRD   neXtProt   phospho.ELM   PhosphoSitePlus   Signor   UniProt 15849194, 17476689, 15705582, ...15972258, 20566643, 10230394, 10949026, 16403219, 18246127, 25681438, 19282669, 15037618, 17663748, 23186163, 20567954, 21419810, 12954615, 10679322, 10558990, 16818649, 10230396, 12897128, 16767165, 20054820, 15226424, 10611223, 18794113, 17270021, 10837486, 11983683, 10880354, 16166315, 11342610, 22506047, 19483729, 20179209, 10521512, 15280015, 14678993, 19667065, 11278822, 9381178
S75 Phosphorylation O75582 (RPS6KA5) neXtProt 11983683, 17663748
S75 Phosphorylation O96013 (PAK4) neXtProt 11278822
S75 Phosphorylation P04049 (RAF1) neXtProt   PhosphoSitePlus   Signor 15849194, 19667065
S75 Phosphorylation P10398 (ARAF) PhosphoSitePlus 19667065
S75 Phosphorylation P11309 (PIM1) HPRD   neXtProt   PhosphoSitePlus   Signor 19483729, 16403219, 15280015
S75 Phosphorylation P15056 (BRAF) neXtProt   PhosphoSitePlus 19667065
S75 Phosphorylation P17612 (PRKACA) PhosphoSitePlus   Signor 10230394, 19667065, 18794113, ...15226424
S75 Phosphorylation P22612 (PRKACG) Signor 10230396, 10949026
S75 Phosphorylation P22694 (PRKACB) Signor 10949026
S75 Phosphorylation P27361 (MAPK3) PhosphoSitePlus 25681438
S75 Phosphorylation P28482 (MAPK1) PhosphoSitePlus 25681438
S75 Phosphorylation P31749 (AKT1) HPRD   neXtProt   Signor 12897128, 10880354, 9381178, ...10521512, 10837486
S75 Phosphorylation P41743 (PRKCI) neXtProt   PhosphoSitePlus   Signor 21419810, 15705582
S75 Phosphorylation P45983 (MAPK8) neXtProt 11983683, 16166315
S75 Phosphorylation P51812 (RPS6KA3) neXtProt   PhosphoSitePlus   Signor 11983683, 10558990, 19282669
S75 Phosphorylation Q02156 (PRKCE) neXtProt   PhosphoSitePlus   Signor 20179209, 20566643
S75 Phosphorylation Q04759 (PRKCQ) neXtProt   PhosphoSitePlus 20179209, 11342610
S75 Phosphorylation Q13153 (PAK1) PhosphoSitePlus   Signor 10611223
S75 Phosphorylation Q15139 (PRKD1) neXtProt   PhosphoSitePlus   Signor 20179209
S75 Phosphorylation Q15349 (RPS6KA2) HPRD   Signor 12897128, 10880354, 10521512, ...10837486, 9381178, 19282669
S75 Phosphorylation Q15418 (RPS6KA1) HPRD   neXtProt   PhosphoSitePlus   Signor 16767165, 12897128, 18246127, ...10880354, 10521512, 14678993, 10679322, 10558990, 9381178, 10837486
S75 Phosphorylation Q86V86 (PIM3) HPRD   neXtProt   PhosphoSitePlus   Signor 16403219, 17270021, 16818649
S75 Phosphorylation Q9NQU5 (PAK6) neXtProt 20054820
S75 Phosphorylation Q9P1W9 (PIM2) HPRD   neXtProt   Signor 12954615, 16403219, 17476689, ...22506047
Y76 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648
T80 Phosphorylation PhosphoSitePlus
S91 Phosphorylation neXtProt   PRO   PhosphoSitePlus   UniProt 11983683, 12049737, 19690332, ...16166315
S91 Phosphorylation P06493 (CDK1) PhosphoSitePlus 16166315
S91 Phosphorylation P45983 (MAPK8) neXtProt 11983683, 16166315
R94 Methylation PhosphoSitePlus   UniProt 21444773
R96 Methylation PhosphoSitePlus   UniProt 21444773
S97 Phosphorylation PhosphoSitePlus
S99 Phosphorylation HPRD   neXtProt   phospho.ELM   PRO   PhosphoSitePlus   Signor   UniProt 10949026, 15705582, 11342610, ...21444773, 16044149, 19667065, 21419810, 11493700, 15037618, 23186163, 10926925, 18669648, 24275569, 11020382, 10679322, 10558990, 10230394, 18220336, 9346240, 15226424, 9651683, 10611223, 11577096, 11983683, 19664994, 20179209, 16403219, 9381178
S99 Phosphorylation P04049 (RAF1) neXtProt   PhosphoSitePlus 19667065
S99 Phosphorylation P10398 (ARAF) PhosphoSitePlus 19667065
S99 Phosphorylation P11309 (PIM1) HPRD   Signor 19664994, 18669648, 9381178, ...16403219, 9651683
S99 Phosphorylation P15056 (BRAF) neXtProt   PhosphoSitePlus 19667065
S99 Phosphorylation P17612 (PRKACA) PhosphoSitePlus   Signor 10230394, 10949026, 19667065
S99 Phosphorylation P22612 (PRKACG) Signor 10949026
S99 Phosphorylation P22694 (PRKACB) Signor 10949026
S99 Phosphorylation P23443 (RPS6KB1) neXtProt 11493700
S99 Phosphorylation P31749 (AKT1) HPRD   neXtProt   PhosphoSitePlus   Signor 21444773, 19664994, 9346240, ...18669648, 19667065, 9651683, 11020382, 10558990, 9381178
S99 Phosphorylation P31751 (AKT2) Signor 10949026
S99 Phosphorylation P41743 (PRKCI) neXtProt   PhosphoSitePlus   Signor 21419810, 15705582
S99 Phosphorylation P51812 (RPS6KA3) neXtProt   PhosphoSitePlus 11983683, 10558990
S99 Phosphorylation Q02156 (PRKCE) PhosphoSitePlus   Signor 20179209
S99 Phosphorylation Q04759 (PRKCQ) neXtProt   PhosphoSitePlus 20179209, 11342610
S99 Phosphorylation Q13153 (PAK1) phospho.ELM   PhosphoSitePlus   Signor 19667065, 10611223
S99 Phosphorylation Q15139 (PRKD1) neXtProt   PhosphoSitePlus   Signor 20179209
S99 Phosphorylation Q15418 (RPS6KA1) neXtProt 10679322
S99 Phosphorylation Q86V86 (PIM3) HPRD   Signor 9381178, 18669648, 19664994, ...16403219, 9651683
S99 Phosphorylation Q9P1W9 (PIM2) HPRD   Signor 9381178, 18669648, 19664994, ...16403219, 9651683
S99 Phosphorylation Q9Y243 (AKT3) Signor 10949026
Y110 Phosphorylation PhosphoSitePlus
S118 Phosphorylation HPRD   neXtProt   phospho.ELM   PhosphoSitePlus   Signor   UniProt 10949026, 15705582, 19667065, ...18707149, 23186163, 20043968, 20179209, 24275569, 10837473, 18794113, 18669648, 10230396, 10230394, 17535812, 9346240, 15226424, 10837486, 19690332, 21419810, 20166139, 16403219
S118 Phosphorylation P04049 (RAF1) neXtProt   PhosphoSitePlus   Signor 19667065, 17535812
S118 Phosphorylation P10398 (ARAF) PhosphoSitePlus 19667065
S118 Phosphorylation P11309 (PIM1) HPRD   Signor 10949026, 18669648, 16403219, ...18707149, 20166139, 10837486
S118 Phosphorylation P15056 (BRAF) neXtProt   PhosphoSitePlus 19667065
S118 Phosphorylation P17612 (PRKACA) HPRD   PhosphoSitePlus   Signor 10230394, 10949026, 18669648, ...19667065, 18707149, 20166139, 18794113, 10837486
S118 Phosphorylation P22612 (PRKACG) Signor 10230396, 10949026
S118 Phosphorylation P22694 (PRKACB) Signor 10949026
S118 Phosphorylation P31749 (AKT1) HPRD   Signor 10949026, 9346240, 18669648, ...18707149, 20166139, 10837486
S118 Phosphorylation P31751 (AKT2) Signor 10949026
S118 Phosphorylation P41743 (PRKCI) neXtProt   PhosphoSitePlus   Signor 21419810, 15705582
S118 Phosphorylation Q02156 (PRKCE) PhosphoSitePlus   Signor 20179209
S118 Phosphorylation Q13153 (PAK1) HPRD   PhosphoSitePlus 10949026, 18669648, 19667065, ...18707149, 20166139, 10837486
S118 Phosphorylation Q13976 (PRKG1) neXtProt 20043968
S118 Phosphorylation Q15139 (PRKD1) neXtProt   PhosphoSitePlus   Signor 20179209
S118 Phosphorylation Q15349 (RPS6KA2) HPRD   Signor 20166139, 18669648, 10949026, ...18707149, 10837486
S118 Phosphorylation Q15418 (RPS6KA1) HPRD   Signor 20166139, 10837486, 18669648, ...10949026, 18707149
S118 Phosphorylation Q86V86 (PIM3) HPRD   Signor 10949026, 18669648, 16403219, ...18707149, 20166139, 10837486
S118 Phosphorylation Q9P1W9 (PIM2) HPRD   Signor 10949026, 10837473, 18669648, ...16403219, 18707149, 20166139, 10837486
S118 Phosphorylation Q9Y243 (AKT3) Signor 10949026
S124 Phosphorylation PhosphoSitePlus
S134 Phosphorylation HPRD   neXtProt   PhosphoSitePlus   UniProt 11717309, 22103330, 16413544, ...24275569, 20166139, 21317286
S134 Phosphorylation P15056 (BRAF) PhosphoSitePlus 21317286
S134 Phosphorylation Q13153 (PAK1) HPRD   PhosphoSitePlus 20166139, 16413544, 21317286
S134 Phosphorylation Q13555 (CAMK2G) neXtProt 22103330
T137 Phosphorylation PhosphoSitePlus
T139 Phosphorylation PhosphoSitePlus
S146 Phosphorylation PhosphoSitePlus
S153 Phosphorylation HPRD   Signor 10837486, 10949026, 16413544, ...10880354
S153 Phosphorylation O75582 (RPS6KA5) HPRD 10880354
S153 Phosphorylation P17612 (PRKACA) HPRD 10837486, 10949026, 10880354
S153 Phosphorylation Q15418 (RPS6KA1) HPRD   Signor 10880354, 10949026, 10837486
R161 Methylation PhosphoSitePlus   UniProt 24129315
Site PTM Type PTM Enzyme Score Source PMID
S75 Phosphorylation PRO 10195903, 16932738
S99 Phosphorylation PRO 10195903, 16932738


Proteoforms

PRO ID (Short Label) Sites PTM Enzyme Source PMID
PR:000046455 (hBAD/Phos:2) pS91 PRO
PR:000046456 (hBAD/Phos:3) pS99 PRO
PR:000026140 (hBAD/iso:2/Phos:1) pS75,pS99 PRO 10195903, 16932738


Proteoform PPIs

Protein 1 Relation Protein 2 Source PMID
PR:000026140 (hBAD/iso:2/Phos:1) Interaction PR:Q08209 (hPPP3CA) PRO 10195903
PR:000026140 (hBAD/iso:2/Phos:1) decreased Interaction PR:Q07817-1 (hBCL2L1/iso:1) PRO 10195903
PR:000026140 (hBAD/iso:2/Phos:1) Interaction PR:P63101 (mYWHAZ) PRO 16932738
PR:000044749 (hBAD/iso:2/UnMod) Interaction PR:Q07817-1 (hBCL2L1/iso:1) PRO 10195903
PR:Q07817-1 (hBCL2L1/iso:1) Interaction PR:Q92934-1 (hBAD/iso:1) PRO 10949026