iPTMnet Report for Q92932 (PTPRN2)
Protein Information
UniProt AC / UniProt ID | Q92932 / PTPR2_HUMAN |
Protein Name | Receptor-type tyrosine-protein phosphatase N2 precursor |
Gene Name | Name: PTPRN2 Synonyms:KIAA0387; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q92932 |
PRO Name | receptor-type tyrosine-protein phosphatase N2 (human) |
Definition | A receptor-type tyrosine-protein phosphatase N2 that is encoded in the genome of human. |
Short Label | hPTPRN2 |
Category | organism-gene |
Q92932 (PTPRN2) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S25 | Phosphorylation | score1 | PhosphoSitePlus | |||
S26 | Phosphorylation | score1 | PhosphoSitePlus | |||
S124 | Phosphorylation | score1 | PhosphoSitePlus | |||
S129 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y139 | Phosphorylation | score1 | PhosphoSitePlus | |||
T199 | Phosphorylation | score1 | PhosphoSitePlus | |||
T220 | O-Glycosylation | score2 | GlyGen PhosphoSitePlus | 23584533 | ||
T220 | Phosphorylation | score1 | PhosphoSitePlus | |||
S230 | O-Glycosylation | score2 | GlyGen PhosphoSitePlus | 23584533 | ||
S230 | Phosphorylation | score1 | PhosphoSitePlus | |||
S247 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y249 | Phosphorylation | score1 | PhosphoSitePlus | |||
S360 | Phosphorylation | score1 | PhosphoSitePlus | |||
T398 | O-Glycosylation | score2 | GlyGen PhosphoSitePlus | 23584533 | ||
S433 | Phosphorylation | score1 | PhosphoSitePlus | |||
S434 | Phosphorylation | score1 | PhosphoSitePlus | |||
S436 | Phosphorylation | score1 | PhosphoSitePlus | |||
S437 | Phosphorylation | score1 | PhosphoSitePlus | |||
T619 | Phosphorylation | score1 | PhosphoSitePlus | |||
S622 | Phosphorylation | score1 | PhosphoSitePlus | |||
S643 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y666 | Phosphorylation | score1 | PhosphoSitePlus | |||
S695 | Phosphorylation | score1 | PhosphoSitePlus | |||
S704 | Phosphorylation | score1 | PhosphoSitePlus | |||
S776 | Phosphorylation | score1 | PhosphoSitePlus | |||
K970 | Acetylation | score2 | PhosphoSitePlus UniProt | 19608861 | ||
T977 | Phosphorylation | score1 | PhosphoSitePlus |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S360 | Phosphorylation | score0 | HPRD | 18702456 | ||
T441 | Phosphorylation | score0 | HPRD | 18702456 |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S124 | R124 | Biomuta | DOID:2531 / hematologic cancer [ cosmic ] | |
T199 | M199 | Biomuta | DOID:1319 / brain cancer [ cosmic, icgc ] DOID:10534 / stomach cancer [ cosmic, icgc ] | |
S247 | C247 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
S343 | Y343 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
S360 | Y360 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
S433 | C433 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
S434 | F434 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
S436 | F436 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] DOID:3571 / liver cancer [ cosmic ] | |
S622 | Y622 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
Y666 | F666 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
S704 | I704 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] | |
S776 | F776 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
S776 | P776 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc, cosmic, icgc ] |