iPTMnet Report for Q92922 (SMARCC1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q92922 / SMRC1_HUMAN
Protein Name SWI/SNF complex subunit SMARCC1
Gene Name Name: SMARCC1
Synonyms:BAF155;
Organism Homo sapiens (Human)

PRO ID PR:Q92922
DAG View
PRO Name SWI/SNF complex subunit SMARCC1 (human)
Definition A SWI/SNF complex subunit SMARCC1 that is encoded in the genome of human.
Short Label hSMARCC1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q92922 (SMARCC1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 22814378
K41 Ubiquitination PhosphoSitePlus
R56 Methylation PhosphoSitePlus
K65 Ubiquitination PhosphoSitePlus
K107 Ubiquitination PhosphoSitePlus
K127 Acetylation PhosphoSitePlus
K129 Ubiquitination PhosphoSitePlus
C164 Methylation IEDB 31844290
Y171 Phosphorylation PhosphoSitePlus
K179 Ubiquitination PhosphoSitePlus
K183 Ubiquitination PhosphoSitePlus
K185 Ubiquitination PhosphoSitePlus
K189 Ubiquitination PhosphoSitePlus
K199 Ubiquitination PhosphoSitePlus
K201 Ubiquitination PhosphoSitePlus
S212 Phosphorylation PhosphoSitePlus
S310 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 17322306, 17287340, 17081983, ...18767875, 19007248, 18452278, 19651622, 18669648, 23186163, 20068231, 19691289
S319 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 17287340, 20068231
S328 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19413330, 21406692, 16083285, ...23186163, 17081983, 18767875, 19664995, 15144186, 19415658, 19651622, 17322306, 18669648, 24275569, 20166139, 17287340, 19690332, 20068231
S330 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19413330, 17322306, 21406692, ...16083285, 17287340, 18212344, 18767875, 19664995, 15144186, 19690332, 19651622, 18669648, 24275569, 20166139, 23186163, 19415658, 20068231, 17081983
T335 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19413330, 21406692, 16083285, ...17287340, 19651622, 18669648, 19415658, 20068231
T337 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 17287340, 17081983, 19651622, ...18669648, 20068231
S339 Phosphorylation HPRD   PhosphoSitePlus 19413330, 19651622
K345 Acetylation PhosphoSitePlus   UniProt 19608861
K346 Acetylation PhosphoSitePlus   UniProt 19608861
S350 Phosphorylation PhosphoSitePlus   UniProt 21406692
Y352 Phosphorylation PhosphoSitePlus
K354 Acetylation PhosphoSitePlus   UniProt 19608861
S357 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19651622, 18669648, 17287340, ...20068231
K359 Acetylation PhosphoSitePlus   UniProt 19608861
K359 Sumoylation PhosphoSitePlus
T368 Phosphorylation PhosphoSitePlus
T375 Phosphorylation PhosphoSitePlus
S395 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 15302935
T398 Phosphorylation HPRD   PhosphoSitePlus   UniProt 21406692, 20068231, 18452278
T404 Phosphorylation HPRD   phospho.ELM 18669648
K421 Ubiquitination PhosphoSitePlus
K428 Ubiquitination PhosphoSitePlus
S434 Phosphorylation PhosphoSitePlus
C462 Methylation IEDB 31844290
K478 Ubiquitination PhosphoSitePlus
K482 Ubiquitination PhosphoSitePlus
S543 Phosphorylation PhosphoSitePlus
T553 Phosphorylation PhosphoSitePlus
S564 Phosphorylation PhosphoSitePlus
S573 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 20068231
K588 Acetylation PhosphoSitePlus
K588 Ubiquitination PhosphoSitePlus
K590 Ubiquitination PhosphoSitePlus
K592 Ubiquitination PhosphoSitePlus
T603 O-Glycosylation GlyGen 23301498, 33214551, 35138101, ...21740066, 34019948, 20305658, 32119511, 28510447, 33465208
Y606 Phosphorylation PhosphoSitePlus
K608 Acetylation PhosphoSitePlus
K644 Ubiquitination PhosphoSitePlus
K716 Ubiquitination PhosphoSitePlus
S723 Phosphorylation PhosphoSitePlus
K739 Ubiquitination PhosphoSitePlus
K740 Ubiquitination PhosphoSitePlus
K750 Ubiquitination PhosphoSitePlus
K792 Acetylation PhosphoSitePlus
K796 Acetylation PhosphoSitePlus
K796 Sumoylation PhosphoSitePlus
S816 Phosphorylation PhosphoSitePlus
S822 Phosphorylation HPRD   PhosphoSitePlus   UniProt 19651622, 21406692
S825 Phosphorylation HPRD   PhosphoSitePlus   UniProt 19651622, 21406692
K829 Sumoylation PhosphoSitePlus
K829 Ubiquitination PhosphoSitePlus
S830 Phosphorylation HPRD   PhosphoSitePlus 19651622
K846 Ubiquitination PhosphoSitePlus
K854 Acetylation PhosphoSitePlus
K856 Ubiquitination PhosphoSitePlus
S876 Phosphorylation PhosphoSitePlus
T879 Phosphorylation PhosphoSitePlus
K880 Ubiquitination PhosphoSitePlus
K882 Ubiquitination PhosphoSitePlus
K893 Ubiquitination PhosphoSitePlus
S894 Phosphorylation PhosphoSitePlus
K905 Ubiquitination PhosphoSitePlus
K906 Ubiquitination PhosphoSitePlus
K910 Ubiquitination PhosphoSitePlus
K925 Ubiquitination PhosphoSitePlus
K948 Acetylation PhosphoSitePlus   UniProt 19608861
K948 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K41 T41 Biomuta DOID:363 / uterine cancer [ icgc ]
S212 * Biomuta DOID:4159 / skin cancer [ cosmic ]
S330 L330 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
T335 A335 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
S339 L339 Biomuta DOID:4159 / skin cancer [ cosmic ]
K345 * Biomuta DOID:1781 / thyroid gland cancer [ cosmic ]
K359 E359 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S434 L434 Biomuta DOID:1324 / lung cancer [ cosmic ]
S434 A434 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]
T553 A553 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K590 N590 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]
Y606 D606 Biomuta DOID:3571 / liver cancer [ cosmic ]
K608 N608 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S723 F723 Biomuta DOID:4159 / skin cancer [ cosmic ]
K854 N854 Biomuta DOID:11054 / urinary bladder cancer [ cosmic ]
K905 N905 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]