iPTMnet Report for Q92843 (BCL2L2)
Protein Information
UniProt AC / UniProt ID | Q92843 / B2CL2_HUMAN |
Protein Name | Bcl-2-like protein 2 |
Gene Name | Name: BCL2L2 Synonyms:BCLW,KIAA0271; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q92843 |
PRO Name | bcl-2-like protein 2 (human) |
Definition | A protein that is a translation product of any of the following genes in human: BCL2L2, or a readthrough of the BCL2L2-PABPN1 genes. |
Short Label | h[BCL2L2/BCL2L2-PABPN1] |
Category | union |
Q92843 (BCL2L2) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
A2 | Acetylation | score1 | UniProt | 19413330 | ||
T172 | Phosphorylation | score1 | PhosphoSitePlus | |||
A177 | Phosphorylation | score1 | UniProt | 18669648, 23186163, 19690332, ... | ||
S192 | Phosphorylation | score1 | PhosphoSitePlus | |||
K193 | Ubiquitination | score1 | PhosphoSitePlus |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
K162 | Ubiquitination | score1 | PhosphoSitePlus | |||
K164 | Ubiquitination | score1 | PhosphoSitePlus | |||
S177 | Phosphorylation | score1 | PhosphoSitePlus | |||
T211 | Phosphorylation | score1 | PhosphoSitePlus | |||
S224 | Phosphorylation | score1 | PhosphoSitePlus | |||
K234 | Acetylation | score1 | PhosphoSitePlus | |||
K234 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y244 | Phosphorylation | score1 | PhosphoSitePlus | |||
K250 | Ubiquitination | score1 | PhosphoSitePlus | |||
R254 | Methylation | score1 | PhosphoSitePlus | |||
R265 | Methylation | score1 | PhosphoSitePlus | |||
R267 | Methylation | score1 | PhosphoSitePlus | |||
R286 | Methylation | score1 | PhosphoSitePlus | |||
R290 | Methylation | score1 | PhosphoSitePlus | |||
R294 | Methylation | score1 | PhosphoSitePlus | |||
R304 | Methylation | score1 | PhosphoSitePlus | |||
R314 | Methylation | score1 | PhosphoSitePlus | |||
S331 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
K164 | N164 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
S224 | L224 | Biomuta | DOID:11054 / urinary bladder cancer [ cosmic, icgc ] | |
R286 | Q286 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] DOID:263 / kidney cancer [ cosmic ] | |
R294 | C294 | Biomuta | DOID:5041 / esophageal cancer [ cosmic ] | |
S331 | F331 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] |