iPTMnet Report for Q92837 (FRAT1)
Protein Information
| UniProt AC / UniProt ID | Q92837 / FRAT1_HUMAN |
| Protein Name | Proto-oncogene FRAT1 |
| Gene Name | Name: FRAT1 |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q92837 |
| PRO Name | proto-oncogene FRAT1 (human) |
| Definition | A proto-oncogene FRAT1 that is encoded in the genome of human. |
| Short Label | hFRAT1 |
| Category | organism-gene |
DAG ViewQ92837 (FRAT1) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| S88 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 19369195 | ||
| S138 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S188 | Phosphorylation | P17612 (PRKACA) , P49841 (GSK3B) , P17252 (PRKCA) | score3 | neXtProt PhosphoSitePlus Signor | 16982607 | |
| K214 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S249 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S279 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S188 | F188 | Biomuta | DOID:10283 / prostate cancer [ cosmic ] | |
| S249 | P249 | Biomuta | DOID:263 / kidney cancer [ cosmic, icgc ] | |
| S279 | R279 | Biomuta | DOID:4362 / cervical cancer [ cosmic, icgc ] |
