Protein Information

Cytoscape View


UniProt AC / UniProt ID Q92819 / HYAS2_HUMAN
Protein Name Hyaluronan synthase 2
Gene Name Name: HAS2
Organism Homo sapiens (Human)

PRO ID PR:Q92819
DAG View
PRO Name hyaluronan synthase 2 (human)
Definition A hyaluronan synthase 2 that is encoded in the genome of human.
Short Label hHAS2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q92819 (HAS2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T77 Phosphorylation PhosphoSitePlus
K80 Ubiquitination PhosphoSitePlus
T110 Phosphorylation PhosphoSitePlus   RLIMS-P   UniProt 21228273, 24134926
T110 Phosphorylation P54646 (PRKAA2) PhosphoSitePlus 21228273
S180 O-Glycosylation GlyGen 30379171, 22887999
K190 Ubiquitination PhosphoSitePlus   UniProt 20507985
T196 Phosphorylation PhosphoSitePlus
S221 O-Glycosylation GlyGen   UniProt 30379171, 22887999
S221 Phosphorylation PhosphoSitePlus
T328 Phosphorylation PhosphoSitePlus   UniProt 32993960
T412 Phosphorylation PhosphoSitePlus
Y546 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T110 A110 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S180 I180 Biomuta DOID:1793 / pancreatic cancer [ icgc ]
S221 L221 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]