Protein Information

Cytoscape View


UniProt AC / UniProt ID Q92800 / EZH1_HUMAN
Protein Name Histone-lysine N-methyltransferase EZH1
Gene Name Name: EZH1
Synonyms:KIAA0388;
Organism Homo sapiens (Human)

PRO ID PR:Q92800
DAG View
PRO Name histone-lysine N-methyltransferase EZH1 (human)
Definition A histone-lysine N-methyltransferase EZH1 that is encoded in the genome of human.
Short Label hEZH1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q92800 (EZH1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K52 Ubiquitination PhosphoSitePlus
K72 Ubiquitination PhosphoSitePlus
K81 Ubiquitination PhosphoSitePlus
S290 Phosphorylation PhosphoSitePlus
Y305 Phosphorylation PhosphoSitePlus
Y319 Phosphorylation PhosphoSitePlus
S388 Phosphorylation PhosphoSitePlus
S416 Phosphorylation PhosphoSitePlus
S490 Phosphorylation PhosphoSitePlus
K570 Ubiquitination PhosphoSitePlus
S665 Phosphorylation PhosphoSitePlus
Y697 Phosphorylation PhosphoSitePlus
K714 Ubiquitination PhosphoSitePlus
K736 Methylation PhosphoSitePlus
K736 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S665 N665 Biomuta DOID:1324 / lung cancer [ cosmic ]