Protein Information

Cytoscape View


UniProt AC / UniProt ID Q92759 / TF2H4_HUMAN
Protein Name General transcription factor IIH subunit 4
Gene Name Name: GTF2H4
Organism Homo sapiens (Human)

PRO ID PR:Q92759
DAG View
PRO Name general transcription factor IIH subunit 4 (human)
Definition A general transcription factor IIH subunit 4 that is encoded in the genome of human.
Short Label hGTF2H4
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q92759 (GTF2H4) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S27 Phosphorylation PhosphoSitePlus
K81 Ubiquitination PhosphoSitePlus
S91 Phosphorylation PhosphoSitePlus
K127 Ubiquitination PhosphoSitePlus
K140 Ubiquitination PhosphoSitePlus
K378 Ubiquitination PhosphoSitePlus
K438 Ubiquitination PhosphoSitePlus
K452 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K127 E127 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
K438 Q438 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]