iPTMnet Report for Q92750 (TAF4B)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q92750 / TAF4B_HUMAN
Protein Name Transcription initiation factor TFIID subunit 4B
Gene Name Name: TAF4B
Synonyms:TAF2C2,TAFII105;
Organism Homo sapiens (Human)

PRO ID PR:Q92750
DAG View
PRO Name transcription initiation factor TFIID subunit 4B (human)
Definition A transcription initiation factor TFIID subunit 4B that is encoded in the genome of human.
Short Label hTAF4B
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q92750 (TAF4B) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T46 O-Glycosylation GlyGen 33214551, 30059200, 35254053, ...34019948, 35289036, 29351928, 28657654, 20068230
R63 Methylation PhosphoSitePlus
S64 Phosphorylation PhosphoSitePlus
R87 Methylation PhosphoSitePlus
T187 O-Glycosylation GlyGen 33214551, 30059200, 35254053, ...34019948, 35289036, 29351928, 28657654, 20068230
T191 O-Glycosylation GlyGen 33214551, 30059200, 35254053, ...34019948, 35289036, 29351928, 28657654, 20068230
Y308 Phosphorylation PhosphoSitePlus
S313 Phosphorylation PhosphoSitePlus
S314 Phosphorylation PhosphoSitePlus
S379 O-Glycosylation GlyGen 33214551, 30059200, 35254053, ...34019948, 35289036, 29351928, 28657654, 20068230
S383 O-Glycosylation GlyGen 33214551, 30059200, 29351928, ...34019948, 30620550, 35289036, 35254053, 28657654, 20068230
T390 O-Glycosylation GlyGen 33214551, 30059200, 35254053, ...34019948, 35289036, 29351928, 28657654, 20068230
T395 Phosphorylation PhosphoSitePlus
S440 O-Glycosylation GlyGen 33214551, 30059200, 35254053, ...34019948, 35289036, 29351928, 28657654, 20068230
T444 O-Glycosylation GlyGen 33214551, 30059200, 35254053, ...34019948, 35289036, 29351928, 28657654, 20068230
S489 O-Glycosylation GlyGen   PhosphoSitePlus 33214551, 30059200, 29351928, ...34019948, 35289036, 35254053, 28657654, 20068230
T502 O-Glycosylation GlyGen 33214551, 30059200, 35254053, ...34019948, 35289036, 29351928, 28657654, 20068230
T502 Phosphorylation PhosphoSitePlus
S516 Phosphorylation PhosphoSitePlus
T553 O-Glycosylation GlyGen 33214551, 30059200, 35254053, ...34019948, 35289036, 29351928, 28657654, 20068230
T561 O-Glycosylation GlyGen 33214551, 30059200, 35254053, ...34019948, 35289036, 29351928, 28657654, 20068230
T570 O-Glycosylation GlyGen 33214551, 30059200, 35254053, ...34019948, 35289036, 29351928, 28657654, 20068230
S571 O-Glycosylation GlyGen 33214551, 30059200, 35254053, ...34019948, 35289036, 29351928, 28657654, 20068230
S595 Phosphorylation PhosphoSitePlus   UniProt 23186163
K599 Ubiquitination PhosphoSitePlus
K670 Ubiquitination PhosphoSitePlus
K731 Ubiquitination PhosphoSitePlus
K799 Ubiquitination PhosphoSitePlus
C836 Methylation IEDB 31844290
Site PTM Type PTM Enzyme Score Source PMID
T570 Phosphorylation HPRD 20068231
S595 Phosphorylation HPRD 19413330, 19664995, 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
R63 Q63 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:3571 / liver cancer [ cosmic ]
R63 L63 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S64 F64 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
R87 W87 Biomuta [ cosmic ]
T187 A187 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
T191 I191 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S314 L314 Biomuta DOID:4159 / skin cancer [ cosmic ]
S379 L379 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:263 / kidney cancer [ cosmic, icgc, tcga ]
S383 Y383 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
T390 N390 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S440 F440 Biomuta DOID:363 / uterine cancer [ icgc ]
S516 P516 Biomuta DOID:3571 / liver cancer [ cosmic ]
T561 M561 Biomuta DOID:363 / uterine cancer [ icgc ]
S571 T571 Biomuta DOID:11054 / urinary bladder cancer [ cosmic ]