iPTMnet Report for Q92686 (NRGN)
Protein Information
UniProt AC / UniProt ID | Q92686 / NEUG_HUMAN |
Protein Name | Neurogranin |
Gene Name | Name: NRGN |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q92686 |
PRO Name | neurogranin (human) |
Definition | A neurogranin that is encoded in the genome of human. |
Short Label | hNRGN |
Category | organism-gene |
Q92686 (NRGN) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
M1 | Acetylation | score1 | UniProt | 19413330 | ||
S36 | Phosphorylation | P05771 (PRKCB) , P17252 (PRKCA) , P05129 (PRKCG) | score4 | HPRD phospho.ELM PhosphoSitePlus RLIMS-P | 10075657, 23462742, 19713936, ... | |
R38 | Methylation | score1 | PhosphoSitePlus | |||
R68 | Methylation | score2 | PhosphoSitePlus UniProt | 24129315 |
PTM-dependent PPI
PTM type | Substrate | Site | Interactant | Association type | Source | PMID | |
---|---|---|---|---|---|---|---|
Phosphorylation | Q92686 (NRGN) | S36 | P0DP23 (CALM1) | inhibited_association | eFIP | 23462742 |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
R38 | Q38 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] | |
R38 | W38 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] |