iPTMnet Report for Q92576 (PHF3)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q92576 / PHF3_HUMAN
Protein Name PHD finger protein 3
Gene Name Name: PHF3
Synonyms:KIAA0244;
Organism Homo sapiens (Human)

PRO ID PR:Q92576
DAG View
PRO Name PHD finger protein 3 (human)
Definition A PHD finger protein 3 that is encoded in the genome of human.
Short Label hPHF3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q92576 (PHF3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S97 Phosphorylation PhosphoSitePlus   UniProt 23186163
T101 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S122 Phosphorylation PhosphoSitePlus
S125 Phosphorylation PhosphoSitePlus   UniProt 23186163
S156 Phosphorylation PhosphoSitePlus
K159 Methylation PhosphoSitePlus
T168 Phosphorylation PhosphoSitePlus
S201 Phosphorylation PhosphoSitePlus
S204 Phosphorylation PhosphoSitePlus
C225 Methylation IEDB 31844290
S256 Phosphorylation PhosphoSitePlus
S283 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 17081983, ...20068231
S289 Phosphorylation PhosphoSitePlus
S299 Phosphorylation PhosphoSitePlus   UniProt 20068231
S342 Phosphorylation PhosphoSitePlus
S345 Phosphorylation PhosphoSitePlus
S359 Phosphorylation PhosphoSitePlus
T387 Phosphorylation PhosphoSitePlus
K395 Ubiquitination PhosphoSitePlus
R471 Methylation PhosphoSitePlus
S473 Phosphorylation phospho.ELM   PhosphoSitePlus 17525332
S476 Phosphorylation PhosphoSitePlus
S488 O-Glycosylation GlyGen 23301498, 27114449, 34019948, ...30379171, 28411811, 29351928, 35132862, 31492838, 35289036, 35254053
K498 Acetylation PhosphoSitePlus
K513 Acetylation PhosphoSitePlus
Y514 Phosphorylation PhosphoSitePlus
K520 Ubiquitination PhosphoSitePlus
S527 O-Glycosylation GlyGen 23301498, 27114449, 34019948, ...30379171, 28411811, 29351928, 35132862, 31492838, 35289036, 35254053
K566 Acetylation PhosphoSitePlus
T579 Phosphorylation PhosphoSitePlus
T584 Phosphorylation PhosphoSitePlus
K590 Acetylation PhosphoSitePlus
T593 Phosphorylation IEDB 32387766
S677 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648, 18220336
S678 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648, 18220336
S680 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 17081983, 20068231
S682 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S702 Phosphorylation PhosphoSitePlus
T715 Phosphorylation PhosphoSitePlus
S752 Phosphorylation PhosphoSitePlus
Y818 Phosphorylation PhosphoSitePlus
T822 Phosphorylation PhosphoSitePlus
S834 Phosphorylation PhosphoSitePlus
S840 Phosphorylation PhosphoSitePlus
K858 Methylation PhosphoSitePlus
S868 O-Glycosylation GlyGen 23301498, 27114449, 34019948, ...30379171, 28411811, 29351928, 35132862, 31492838, 35289036, 35254053
S868 Phosphorylation PhosphoSitePlus
S869 Phosphorylation PhosphoSitePlus
K872 Acetylation PhosphoSitePlus
K875 Acetylation PhosphoSitePlus
K878 Acetylation PhosphoSitePlus
K921 Acetylation PhosphoSitePlus
K961 Ubiquitination PhosphoSitePlus
K964 Sumoylation PhosphoSitePlus
K964 Ubiquitination PhosphoSitePlus
K989 Ubiquitination PhosphoSitePlus
T1006 Phosphorylation PhosphoSitePlus
S1014 Phosphorylation PhosphoSitePlus   UniProt 23186163
K1021 Ubiquitination PhosphoSitePlus
T1034 Phosphorylation PhosphoSitePlus
T1054 Phosphorylation PhosphoSitePlus
S1063 Phosphorylation PhosphoSitePlus
S1084 Phosphorylation PhosphoSitePlus
C1118 Methylation IEDB 31844290
S1133 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 23186163, 15302935, ...18669648, 24275569, 20068231
S1148 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 24275569
S1154 Phosphorylation PhosphoSitePlus
S1163 Phosphorylation PhosphoSitePlus
S1168 Phosphorylation phospho.ELM 18669648
S1178 Phosphorylation IEDB   phospho.ELM   PhosphoSitePlus   UniProt 35561310, 32157095, 18669648, ...27869121, 24275569, 19690332, 20068231
S1181 Phosphorylation PhosphoSitePlus
T1182 Phosphorylation PhosphoSitePlus
S1184 Phosphorylation phospho.ELM   PhosphoSitePlus 18220336
T1194 Phosphorylation PhosphoSitePlus
C1270 Methylation IEDB 31844290
Y1298 Phosphorylation PhosphoSitePlus
Y1312 Phosphorylation PhosphoSitePlus
T1319 Phosphorylation PhosphoSitePlus
S1356 Phosphorylation PhosphoSitePlus
S1401 Phosphorylation PhosphoSitePlus
T1516 Phosphorylation PhosphoSitePlus
S1588 Phosphorylation PhosphoSitePlus
S1613 Phosphorylation PhosphoSitePlus
S1614 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 16964243, 17081983
S1618 Phosphorylation PhosphoSitePlus
S1630 Phosphorylation PhosphoSitePlus
T1639 Phosphorylation PhosphoSitePlus
S1642 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 16964243, ...20068231
K1649 Ubiquitination PhosphoSitePlus
T1664 O-Glycosylation GlyGen 27114449
S1703 Phosphorylation PhosphoSitePlus
S1708 Phosphorylation PhosphoSitePlus
S1722 O-Glycosylation GlyGen 23301498, 27114449, 34019948, ...30379171, 28411811, 29351928, 35132862, 31492838, 35289036, 35254053
S1722 Phosphorylation PhosphoSitePlus
S1724 O-Glycosylation GlyGen 23301498, 27114449, 34019948, ...30379171, 28411811, 29351928, 35132862, 31492838, 35289036, 35254053
S1724 Phosphorylation PhosphoSitePlus
S1731 Phosphorylation PhosphoSitePlus
R1756 Methylation PhosphoSitePlus
S1758 O-Glycosylation GlyGen 23301498, 34846842, 27114449, ...28411811, 30379171, 34019948, 29351928, 35132862, 31492838, 35289036, 35254053
S1758 Phosphorylation PhosphoSitePlus
S1763 O-Glycosylation GlyGen 32938750
S1763 Phosphorylation PhosphoSitePlus
T1770 O-Glycosylation GlyGen 23301498, 27114449, 28411811, ...30379171, 32938750, 34019948, 29351928, 35132862, 31492838, 35289036, 35254053
S1773 O-Glycosylation GlyGen 23301498, 34846842, 27114449, ...28411811, 30379171, 34019948, 29351928, 35132862, 31492838, 35289036, 35254053
S1777 O-Glycosylation GlyGen 34846842
S1784 Phosphorylation PhosphoSitePlus
R1785 Methylation PhosphoSitePlus
S1786 O-Glycosylation GlyGen 23301498, 27114449, 34019948, ...30379171, 28411811, 29351928, 35132862, 31492838, 35289036, 35254053
S1788 O-Glycosylation GlyGen 30379171
R1790 Methylation PhosphoSitePlus
T1791 O-Glycosylation GlyGen 30379171
S1792 O-Glycosylation GlyGen 30379171
T1793 O-Glycosylation GlyGen 30379171
S1796 O-Glycosylation GlyGen 30379171
S1796 Phosphorylation PhosphoSitePlus
R1799 Methylation PhosphoSitePlus
K1809 Methylation PhosphoSitePlus
R1867 Methylation PhosphoSitePlus   UniProt 24129315
R1877 Methylation PhosphoSitePlus   UniProt 24129315
S1898 Phosphorylation PhosphoSitePlus   UniProt 24275569
R1911 Methylation PhosphoSitePlus
R1915 Methylation PhosphoSitePlus
K1917 Methylation PhosphoSitePlus
R1922 Methylation PhosphoSitePlus
Y1924 Phosphorylation PhosphoSitePlus
S1925 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 18220336
S1927 Phosphorylation PhosphoSitePlus
S1952 Phosphorylation PhosphoSitePlus
S1975 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S97 Phosphorylation HPRD 20068231
T101 Phosphorylation HPRD 18669648
S283 Phosphorylation HPRD 19413330, 18669648, 17081983, ...20068231
S299 Phosphorylation HPRD 20068231
T387 Phosphorylation HPRD 20068231
S473 Phosphorylation HPRD 17525332
S677 Phosphorylation HPRD 18669648, 20068231
S678 Phosphorylation HPRD 18669648, 20068231
S680 Phosphorylation HPRD 18669648, 15345747, 20068231, ...18452278
S682 Phosphorylation HPRD 18669648, 20068231, 18452278
S1133 Phosphorylation HPRD 19413330, 20058876, 18212344, ...15302935, 19664994, 19664995, 19651622, 18669648, 19415658, 20068231
S1148 Phosphorylation HPRD 18669648, 18452278
S1154 Phosphorylation HPRD 18452278
T1162 Phosphorylation HPRD 17081983
S1168 Phosphorylation HPRD 18669648
S1178 Phosphorylation HPRD 18669648, 20068231, 18452278
S1568 Phosphorylation HPRD 20068231
S1611 Phosphorylation HPRD 17081983
S1613 Phosphorylation HPRD 17081983, 20068231, 19664995
S1614 Phosphorylation HPRD 19413330, 19664994, 16964243, ...20068231, 19664995
S1618 Phosphorylation HPRD 19413330
S1642 Phosphorylation HPRD 19651622, 18669648, 19664994, ...20068231
S1722 Phosphorylation HPRD 19413330, 20068231
S1724 Phosphorylation HPRD 19413330
S1898 Phosphorylation HPRD 20068231
S1925 Phosphorylation HPRD 20068231
S1927 Phosphorylation HPRD 17081983


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T101 A101 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S125 F125 Biomuta [ cosmic ]
K159 N159 Biomuta DOID:9256 / colorectal cancer [ icgc ]
T168 I168 Biomuta DOID:1324 / lung cancer [ cosmic ]
S204 N204 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S289 L289 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S289 * Biomuta DOID:1324 / lung cancer [ cosmic ]
S299 F299 Biomuta DOID:4159 / skin cancer [ cosmic ]
S342 F342 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S345 F345 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S359 N359 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S476 I476 Biomuta DOID:4159 / skin cancer [ cosmic ]
S488 F488 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:1319 / brain cancer [ cosmic ]
K498 N498 Biomuta DOID:4606 / bile duct cancer [ cosmic ]
S527 I527 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S680 I680 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S702 F702 Biomuta DOID:4159 / skin cancer [ cosmic ]
S840 * Biomuta DOID:4606 / bile duct cancer [ cosmic ]
S1084 * Biomuta DOID:11054 / urinary bladder cancer [ cosmic ]
S1133 C1133 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]
T1182 M1182 Biomuta DOID:1324 / lung cancer [ cosmic ]
S1184 F1184 Biomuta DOID:1612 / breast cancer [ cosmic ]
Y1298 C1298 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S1401 Y1401 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
S1401 F1401 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ] DOID:8618 / oral cavity cancer [ cosmic ]
S1401 C1401 Biomuta DOID:11054 / urinary bladder cancer [ cosmic ]
S1611 L1611 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S1618 C1618 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S1630 R1630 Biomuta DOID:5041 / esophageal cancer [ cosmic ]
S1642 F1642 Biomuta DOID:1612 / breast cancer [ cosmic ] DOID:3571 / liver cancer [ cosmic ]
S1708 L1708 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
S1708 * Biomuta DOID:4159 / skin cancer [ cosmic ]
S1722 * Biomuta DOID:263 / kidney cancer [ cosmic ]
S1758 L1758 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S1758 * Biomuta DOID:10534 / stomach cancer [ cosmic ]
S1788 N1788 Biomuta DOID:4606 / bile duct cancer [ cosmic ]
S1792 T1792 Biomuta DOID:1324 / lung cancer [ cosmic ]
S1796 L1796 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
R1867 H1867 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
R1877 K1877 Biomuta DOID:4159 / skin cancer [ cosmic ]
S1898 N1898 Biomuta DOID:184 / bone cancer [ cosmic ]
R1922 I1922 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S1952 G1952 Biomuta DOID:10534 / stomach cancer [ cosmic ]