iPTMnet Report for Q8WYL5 (SSH1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8WYL5 / SSH1_HUMAN
Protein Name Protein phosphatase Slingshot homolog 1
Gene Name Name: SSH1
Synonyms:KIAA1298,SSH1L;
Organism Homo sapiens (Human)

PRO ID PR:Q8WYL5
DAG View
PRO Name protein phosphatase Slingshot homolog 1 (human)
Definition A protein phosphatase Slingshot homolog 1 that is encoded in the genome of human.
Short Label hSSH1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8WYL5 (SSH1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 19413330
T5 Phosphorylation PhosphoSitePlus
S9 Phosphorylation PhosphoSitePlus
T11 Phosphorylation PhosphoSitePlus
S37 Phosphorylation PhosphoSitePlus   UniProt 20068231
S57 Phosphorylation PhosphoSitePlus   UniProt 20068231
S261 Phosphorylation PhosphoSitePlus
S400 Phosphorylation PhosphoSitePlus
S402 Phosphorylation Q15139 (PRKD1) neXtProt   PhosphoSitePlus 21525957
T403 Phosphorylation PhosphoSitePlus
Y407 Phosphorylation PhosphoSitePlus
S428 Phosphorylation PhosphoSitePlus
T430 Phosphorylation PhosphoSitePlus
S441 Phosphorylation PhosphoSitePlus
Y443 Phosphorylation PhosphoSitePlus
K456 Ubiquitination PhosphoSitePlus
T462 Phosphorylation PhosphoSitePlus
S464 Phosphorylation PhosphoSitePlus
S465 Phosphorylation PhosphoSitePlus
S515 Phosphorylation PhosphoSitePlus
S521 Phosphorylation PhosphoSitePlus
T526 Phosphorylation PhosphoSitePlus
S576 Phosphorylation PhosphoSitePlus   UniProt 23186163
S583 Phosphorylation PhosphoSitePlus
T590 Phosphorylation PhosphoSitePlus
S645 Phosphorylation PhosphoSitePlus
Y646 Phosphorylation PhosphoSitePlus
K758 Methylation PhosphoSitePlus
S812 Phosphorylation PhosphoSitePlus
T826 Phosphorylation P31749 (AKT1) PhosphoSitePlus   RLIMS-P 25100728
S834 Phosphorylation PhosphoSitePlus
S854 Phosphorylation PhosphoSitePlus
S889 Phosphorylation PhosphoSitePlus
S894 Phosphorylation PhosphoSitePlus
S897 Phosphorylation PhosphoSitePlus   UniProt 23186163
T908 Phosphorylation PhosphoSitePlus
S910 Phosphorylation PhosphoSitePlus
T922 Phosphorylation PhosphoSitePlus
T933 Phosphorylation PhosphoSitePlus
S935 Phosphorylation PhosphoSitePlus
S936 Phosphorylation PhosphoSitePlus
S937 Phosphorylation Q9BZL6 (PRKD2) , Q15139 (PRKD1) , Q13557 (CAMK2D) neXtProt   phospho.ELM   PhosphoSitePlus   RLIMS-P   Signor 22270398, 15159416, 21525957, ...18669648, 19329994, 19567672
S938 Phosphorylation PhosphoSitePlus
S940 Phosphorylation PhosphoSitePlus
S943 Phosphorylation PhosphoSitePlus
K952 Acetylation PhosphoSitePlus
S970 Phosphorylation PhosphoSitePlus
S971 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S978 Phosphorylation Q13557 (CAMK2D) , Q15139 (PRKD1) , Q9BZL6 (PRKD2) neXtProt   phospho.ELM   PhosphoSitePlus   RLIMS-P   Signor   UniProt 24840177, 15159416, 22270398, ...21525957, 19329994, 19567672
T1021 Phosphorylation PhosphoSitePlus
K1041 Methylation PhosphoSitePlus
S1042 Phosphorylation phospho.ELM   PhosphoSitePlus 15302935
Site PTM Type PTM Enzyme Score Source PMID
T5 Phosphorylation HPRD 20068231
S37 Phosphorylation HPRD 20068231
S57 Phosphorylation HPRD 20068231
S515 Phosphorylation HPRD 20058876
S576 Phosphorylation HPRD 20068231
S937 Phosphorylation HPRD 18669648
S971 Phosphorylation HPRD 18669648, 20068231
S976 Phosphorylation HPRD 20068231
Site PTM Type PTM Enzyme Score Source PMID
S644 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S261 G261 Biomuta DOID:3571 / liver cancer [ cosmic ]
S400 L400 Biomuta DOID:10283 / prostate cancer [ cosmic, icgc ]
T430 R430 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
Y443 C443 Biomuta DOID:3571 / liver cancer [ cosmic, icgc ]
K456 N456 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
S576 G576 Biomuta DOID:1612 / breast cancer [ cosmic ]
T590 M590 Biomuta DOID:363 / uterine cancer [ icgc ] DOID:8618 / oral cavity cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ]
S645 F645 Biomuta DOID:4159 / skin cancer [ cosmic ]
T922 I922 Biomuta DOID:4159 / skin cancer [ cosmic ]
S940 N940 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S970 F970 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S971 F971 Biomuta DOID:1324 / lung cancer [ cosmic ]