iPTMnet Report for Q8WY54 (PPM1E)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8WY54 / PPM1E_HUMAN
Protein Name Protein phosphatase 1E
Gene Name Name: PPM1E
Synonyms:CAMKN,KIAA1072,POPX1;
Organism Homo sapiens (Human)

PRO ID PR:Q8WY54
DAG View
PRO Name protein phosphatase 1E (human)
Definition A protein phosphatase 1E that is encoded in the genome of human.
Short Label hPPM1E
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8WY54 (PPM1E) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S176 Phosphorylation PhosphoSitePlus
S179 Phosphorylation PhosphoSitePlus
Y182 Phosphorylation PhosphoSitePlus
T193 Phosphorylation PhosphoSitePlus
K200 Ubiquitination PhosphoSitePlus
S400 Phosphorylation PhosphoSitePlus
S501 Phosphorylation PhosphoSitePlus
T504 Phosphorylation PhosphoSitePlus
S507 Phosphorylation PhosphoSitePlus
S535 Phosphorylation PhosphoSitePlus
S548 Phosphorylation PhosphoSitePlus
Y674 Phosphorylation PhosphoSitePlus
S675 Phosphorylation PhosphoSitePlus
S710 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S179 P179 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S501 * Biomuta DOID:1612 / breast cancer [ cosmic ]
S548 L548 Biomuta DOID:4159 / skin cancer [ cosmic ]
S675 L675 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S710 N710 Biomuta [ cosmic ]